| Entry | 催化剂 | 氧化剂 | 添加物 | 溶剂 | 产率/%a |
| 1b | Pd(acac)2 | AgOAc | —— | ClCH2CH2Cl | 16 |
| 2 | Pd(acac)2 | AgNO3 | —— | ClCH2CH2Cl | 13 |
| 3 | Pd(acac)2 | AgCO3 | —— | ClCH2CH2Cl | — |
| 4 | Pd(acac)2 | AgF | —— | ClCH2CH2Cl | 23 |
| 5 | Pd(acac)2 | PhI(OAc)2 | —— | ClCH2CH2Cl | — |
| 6 | Pd(acac)2 | Cu(OAc)2 | —— | ClCH2CH2Cl | 28 |
| 7 | Pd(OAc)2 | Cu(OAc)2 | —— | ClCH2CH2Cl | 21 |
| 8 | Pd[P(Ph)3]2Cl2 | Cu(OAc)2 | —— | ClCH2CH2Cl | 痕量 |
| 9 | Pd(acac)2 | Cu(OAc)2 | —— | 乙醇 | — |
| 10 | Pd(acac)2 | Cu(OAc)2 | —— | DMSO | 痕量 |
| 11 | Pd(acac)2 | Cu(OAc)2 | —— | DMF | — |
| 12 | Pd(acac)2 | Cu(OAc)2 | —— | EtOAc | 35 |
| 13 | Pd(acac)2 | Cu(OAc)2 | —— | NMP | 14 |
| 14 | Pd(acac)2 | Cu(OAc)2 | —— | THF | 28 |
| 15b | Pd(acac)2 | Cu(OAc)2 | —— | EtOAc | 45 |
| 16c | Pd(acac)2 | Cu(OAc)2 | —— | EtOAc | 55 |
| 17d | Pd(acac)2 | Cu(OAc)2 | —— | EtOAc | 53 |
| 18 | Pd(acac)2 | Cu(OAc)2 | 三氟乙酸 | EtOAc | 33 |
| 19 | Pd(acac)2 | Cu(OAc)2 | KOtBu | EtOAc | — |
| 20 | Pd(acac)2 | Cu(OAc)2 | KHCO3 | EtOAc | 15 |
| 21 | Pd(acac)2 | Cu(OAc)2 | 对苯醌 | EtOAc | 33 |
| 22 | Pd(acac)2 | Cu(OAc)2 | 苯甲酸 | EtOAc | 54 |
| 23 | Pd(acac)2 | Cu(OAc)2 | AgF | EtOAc |
|
| 24 | Pd(acac)2 | Cu(OAc)2 | AgF (0.3 eq.) | EtOAc | 78 |
| 26 | Pd(acac)2 | Cu(OAc)2 | CsF | EtOAc | 57 |
| 27 | —— | Cu(OAc)2 | AgF | EtOAc | — |