变量

乳酸脱氢酶，U/L

Q1组 ≤ 149 (n = 1228)

Q2组149~177.5 (n = 1227)

Q3组177.5~222.5 (n = 1227)

Q4组 < 222.5 (n = 1227)

P

年龄，岁

60.24 ± 14.40

62.07 ± 13.21

62.79 ± 13.82

60.38 ± 15.11

<0.001

男性(N, %)

780 (63.52%)

715 (58.27%)

689 (56.15%)

688 (56.07%)

<0.001

体重指数，kg/m²

23.84 ± 3.58

24.38 ± 3.65

24.54 ± 3.78

24.33 ± 3.94

<0.001

收缩压，mmHg

129.69 ± 18.81

131.72 ± 18.62

134.67 ± 21.02

131.58 ± 21.68

<0.001

舒张压，mmHg

76.55 ± 12.01

77.04 ± 11.56

77.73 ± 12.05

77.19 ± 13.67

0.126

手术史(N, %)

610 (49.67%)

552 (44.99%)

498 (40.59%)

513 (41.81%)

<0.001

吸烟史(N, %)

460 (37.46%)

455 (37.08%)

424 (34.56%)

383 (31.21%)

0.004

饮酒史(N, %)

399 (32.49%)

348 (28.36%)

329 (26.81%)

328 (26.73%)

0.004

红细胞计数，×10¹²/L

4.15 ± 0.74

4.24 ± 0.73

4.24 ± 0.71

3.98 ± 0.81

<0.001

白细胞计数，×10⁹/L

6.38 ± 2.66

6.49 ± 2.63

6.91 ± 2.92

7.99 ± 3.59

<0.001

血红蛋白，g/L

120.94 ± 25.25

126.49 ± 23.46

126.56 ± 23.07

119.12 ± 25.35

<0.001

血小板，×10⁹/L

233.82 ± 92.74

223.86 ± 84.66

220.67 ± 87.62

202.72 ± 95.66

<0.001

凝血酶原时间，s

11.03 ± 1.64

10.84 ± 1.56

11.19 ± 1.79

11.95 ± 2.05

<0.001

纤维蛋白原，g/L

3.42 ± 1.14

3.38 ± 1.05

3.47 ± 1.10

3.65 ± 1.32

<0.001

凝血酶时间，s

15.73 ± 2.22

15.62 ± 2.24

15.86 ± 2.44

16.16 ± 2.68

<0.001

白蛋白，g/L

36.82 ± 6.13

38.12 ± 5.89

37.38 ± 6.57

34.68 ± 7.29

<0.001

谷丙转氨酶，U/L

19.34 ± 14.87

19.66 ± 12.70

21.84 ± 14.71

26.87 ± 17.40

<0.001

谷草转氨酶，U/L

17.82 ± 9.75

19.25 ± 8.61

22.02 ± 10.94

28.70 ± 13.94

<0.001

总胆红素，μmol/L

13.63 ± 6.91

14.57 ± 6.71

15.54 ± 7.61

16.91 ± 9.09

<0.001

葡萄糖，mmol/L

5.39 ± 1.47

5.46 ± 1.60

5.67 ± 1.68

5.86 ± 1.86

<0.001

总胆固醇，mmol/L

4.56 ± 1.30

4.77 ± 1.29

4.79 ± 1.38

4.69 ± 1.55

<0.001

甘油三酯，mmol/L

1.23 ± 0.65

1.29 ± 0.66

1.30 ± 0.68

1.36 ± 0.75

<0.001

尿酸，μmol/L

273.98 ± 92.88

280.59 ± 95.99

285.42 ± 105.05

291.50 ± 132.05

0.001

血肌酐，μmol/L

69.89 ± 24.23

69.54 ± 24.64

70.79 ± 26.43

73.71 ± 29.87

<0.001

eGFR, ml/min/1.73m²

92.05 ± 24.57

90.52 ± 23.41

88.41 ± 26.02

86.19 ± 31.57

<0.001

CKD (N, %)

25 (2.04%)

30 (2.44%)

47 (3.83%)

103 (8.39%)

<0.001

脑梗死(N, %)

62 (5.05%)

64 (5.22%)

71 (5.79%)

78 (6.36%)

0.483

糖尿病(N, %)

208 (16.94%)

200 (16.30%)

187 (15.24%)

190 (15.48%)

0.647

冠心病(N, %)

180 (14.66%)

204 (16.63%)

225 (18.34%)

202 (16.46%)

0.110

高血压(N, %)

329 (26.79%)

380 (30.97%)

407 (33.17%)

368 (29.99%)

0.007

质子泵抑制剂(N, %)

1059 (86.24%)

1070 (87.20%)

1043 (85.00%)

1060 (86.39%)

0.465

ACEI/ARB (N, %)

667 (54.32%)

695 (56.64%)

706 (57.54%)

639 (52.08%)

0.030

利尿剂(N, %)

1013 (82.49%)

1011 (82.40%)

1014 (82.64%)

1009 (82.23%)

0.995

β受体阻滞剂(N, %)

556 (45.28%)

530 (43.19%)

529 (43.11%)

497 (40.51%)

0.125

钙通道阻滞剂(N, %)

255 (20.77%)

314 (25.59%)

392 (31.95%)

415 (33.82%)

<0.001

抗生素(N, %)

897 (73.05%)

867 (70.66%)

882 (71.88%)

932 (75.96%)

0.023

非甾体类抗炎药(N, %)

474 (38.60%)

473 (38.55%)

388 (31.62%)

236 (19.23%)

<0.001

AKI (0期)

1069 (87.05%)

1062 (86.55%)

1005 (81.91%)

923 (75.22%)

<0.001

AKI (1期)

136 (11.07%)

139 (11.33%)

180 (14.67%)

225 (18.34%)

AKI (2期)

16 (1.30%)

16 (1.30%)

32 (2.61%)

53 (4.32%)

AKI (3期)

7 (0.57%)

10 (0.81%)

10 (0.81%)

26 (2.12%)

住院时间，天

17.21 ± 7.61

17.39 ± 7.87

17.83 ± 8.08

19.11 ± 9.25

<0.001

死亡(N, %)

12 (0.98%)

17 (1.39%)

27 (2.20%)

69 (5.62%)

<0.001