Author | Type | Number | Age range | 68Ga-FAPI dose | 18F-FDG dose | Two-scan interval | FAPI SUVmax | FDG SUVmax | Conclusion (FAPI ·VS· FDG) |
Siwen Qiu | Case report | 1 | - | - | - | 1 day | 8.4 | 2.5 | FAPI > FDG |
Halil Kömek | Case report | 1 | - | - | - | - | 5.3 | N | FAPI > FDG |
Halil Kömek | Clinical research | 20 | 32~65 | 2 MBq/kg | 3.5~5.5 MBq/kg | 1 week | - | - | 1. Insensitivity (100% vs 78.2%) 2. Higher SUVmax、 Higher TBR 3. Low physiological uptake of liver, brain and bone |
Umut Elboga | Clinical research | 48 | 53.3 ± 11.7 | 2 MBq/kg | 3.5~5.5 MBq/kg | 1 week | 10.0 (median 2.6-17.0) | 3.1 (median1.1-13.2) | 1. FAPI detected more lesions in the breast 2. PBC has a higher FAPI SUVmax value |
Katharina Dendl | Clinical research | 14 | 59.5 (median) | 52~325 MBq | 251~300 MBq | 12.5 day (median) | 7.1 (Lymph node) 10.1 (Bone metastases) | 6.3 (Lymph node) 7.4 (Bone metastases) | 1. PBC has stronger FAPI uptake than MBC 2. In metastatic lesions, FAPI has a significant advantage |