| Variables | Univariate p valuea | Multivariate | ||
| HR | 95% CI | p valueb | ||
| Age:>53 vs. ≤53 (years) | 0.991 |
|
| NA |
| Gender: male vs. female | 0.085 |
|
| NA |
| CA19-9: >100 vs. ≤100 | 0.073 |
|
| NA |
| Hepatitis: yes vs. no | 0.979 |
|
| NA |
| Liver cirrhosis: yes vs. no | 0.059 |
|
| NA |
| Tumor number: multiple vs. solitary | 0.002 | 2.148 | 1.065~4.329 | 0.033 |
| Tumor size: >5 vs. ≤5 (cm) | 0.035 |
|
| NS |
| Tumor differentiation: I+II/III+IV | 0.070 |
|
| NA |
| Lymph node metastasis: yes vs. no | 0.006 |
|
| NS |
| TNM stage: I+II/IIIA+IIIB+IIIC | 0.001 | 2.230 | 1.077~4.620 | 0.031 |
| TGF-β1: high vs. low | 0.012 | 2.258 | 1.179~4.324 | 0.014 |
| ALDH1: high vs. low | 0.033 |
|
| NS |