抑郁评分量表 | 时长(周) | 研究数量 | 例数 (实验组/ 对照组) | 效应 模型 | 综合 效应值 | 置信区间/95% CI | P-value | 组间异质性 |
HAMD | 1 | 2 | 90/88 | RE | SMD = −2.20 | (−3.13, −1.29) | < 0.00001 | I2 = 51.6%, P = 0.07 |
2 | 7 | 315/325 | RE | SMD = −0.97 | (−1.55, −0.39) | 0.001 | ||
4 | 14 | 596/576 | RE | SMD = −1.24 | (−1.65, −0.83) | < 0.00001 | ||
6 | 10 | 510/518 | RE | SMD = −1.04 | (−1.42, −0.66) | < 0.00001 | ||
8 | 6 | 232/214 | RE | SMD = −1.22 | (−1.94, −0.50) | 0.0009 | ||
12 | 4 | 127/127 | RE | SMD = −2.58 | (−3.87, −1.29) | < 0.0001 | ||
EPDS | 1 | 1 | 25/24 | RE | SMD = −0.53 | (−1.11, 0.04) | 0.07 | I2 = 70.5%, P = 0.005 |
2 | 2 | 113/125 | RE | SMD = −0.32 | (−0.79, 0.14) | 0.17 | ||
4 | 1 | 45/52 | RE | SMD = −0.30 | (−0.72, 0.11) | 0.15 | ||
EPDS | 6 | 3 | 138/149 | RE | SMD = −0.79 | (−1.15, −0.43) | < 0.0001 | I2 = 70.5%, P = 0.005 |
8 | 2 | 78/90 | RE | SMD = −1.36 | (−1.77, −0.94) | < 0.00001 | ||
12 | 1 | 25/24 | RE | SMD = −0.95 | (−1.54, −036) | < 0.002 | ||
HAMA | 2 | 3 | 155/155 | RE | SMD = −1.02 | (−1.26, −0.78) | < 0.00001 | I2 = 80.3%, P = 0.0004 |
4 | 2 | 83/73 | RE | SMD = −1.95 | (−2.35, −1.55) | < 0.00001 | ||
6 | 2 | 115/115 | RE | SMD = −1.68 | (−3.23, −0.13) | 0.03 | ||
8 | 2 | 82/82 | RE | SMD = −0.94 | (−1.65, −0.22) | 0.01 | ||
12 | 2 | 77/67 | RE | SMD = −3.04 | (−4.78, −1.31) | 0.0006 |