临床参数

p

ALK (n = 104)

EGFR (n = 113)

Non-ALK/EGFR (n = 59)

ALK vs EGFR

ALK vs Non-ALK/EGFR

年龄(岁)

≥60

38 (36.5%)

67 (59.3%)

37 (62.7%)

0.001

0.001

<60

66 (63.5%)

46 (40.7%)

22 (37.3%)

性别

男

40 (38.5%)

32 (28.3%)

15 (25.4%)

0.113

<0.001

女

64 (61.5%)

81 (71.7%)

44 (74.6%)

吸烟史

无

83 (79.8%)

89 (78.8%)

24 (40.7%)

0.849

<0.001

有

21 (20.2%)

24 (21.2%)

35 (59.3%)

病理类型

腺癌

104 (100.0%)

106 (93.8%)

53 (89.8%)

0.015^a

0.002^a

其他

0 (0.0%)

7 (6.2%)

6 (10.2%)

标本类型

手术标本

60 (57.7%)

80 (70.8%)

37 (62.7%)

0.079

0.072

活检小标本

16 (15.4%)

19 (16.8%)

16 (27.1%)

纤支镜活检

11 (10.6%)

5 (4.4%)

3 (5.1%)

淋巴结活检

6 (5.7%)

5 (4.4%)

2 (3.4%)

其他

11 (10.6%)

4 (3.6%)

1 (1.7%)

原发部位

中央型

16 (15.4%)

11 (9.7%)

14 (23.7%)

0.208

0.186

周围型

88 (84.6%)

102 (90.3%)

45 (76.3%)

转移情况

无

30 (28.8%)

48 (42.5%)

23 (39.0%)

0.037

0.184

有

74 (71.2%)

65 (57.5%)

36 (61.0%)

TNM分期

I、II

41 (39.4%)

60 (53.1%)

33 (55.9%)

0.044

0.042

III、IV

63 (60.6%)

53 (46.9%)

26 (44.1%)