变量 | 数量 | 癌胚抗原 (+) N (%) | P value | CA199 (+) N (%) | P value | CA72-4 (+) N (%) | P value | Combined detection (+) N (%) | P value |
性别: |
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男 | 69 | 34 (49.2) |
| 18 (26.0) |
| 23 (33.3) |
| 48 (69.5) |
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女 | 21 | 8 (38) | 0.369 | 5 (23.8) | 0.834 | 9 (42.8) | 0.425 | 15 (71.4) | 0.870 |
年龄(岁): |
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≤60 | 34 | 18 (52.9) |
| 9 (26.4) |
| 14 (41.1) |
| 26 (76.4) |
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>60 | 56 | 24 (42.8) | 0.353 | 14 (25.0) | 0.877 | 18 (32.1) | 0.385 | 37 (66.0) | 0.297 |
分化程度: |
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分化较好 | 38 | 11 (28.9) |
| 7 (18.4) |
| 10 (26.3) |
| 22 (57.8) |
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分化不良 | 52 | 31 (59.6) | 0.004 | 16 (30.7) | 0.185 | 22 (42.3) | 0.117 | 41 (78.8) | 0.032 |
肿瘤直径: |
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≤4 cm | 80 | 36 (45.0) |
| 22 (27.5) |
| 25 (31.2) |
| 55 (68.7) |
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>4 cm | 10 | 6 (60) | 0.575 | 1 (10) | 0.417 | 7 (70) | 0.039 | 8 (80) | 0.714 |
浸润深度: |
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T1 + T2 | 36 | 13 (36.1) |
| 6 (16.6) |
| 14 (38.8) |
| 22 (61.1) |
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T3 + T4 | 54 | 29 (53.7) | 0.101 | 17 (31.4) | 0.114 | 18 (33.3) | 0.590 | 41 (75.9) | 0.133 |
淋巴结转移数: |
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N0 + N1 | 49 | 18 (36.7) |
| 10 (20.4) |
| 15 (30.6) |
| 29 (59.1) |
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N2 + N3 | 41 | 24 (58.5) | 0.039 | 13 (31.7) | 0.221 | 17 (41.4) | 0.284 | 34 (82.9) | 0.014 |
TNM分期: |
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I + II | 34 | 12 (35.2) |
| 5 (14.7) |
| 7 (20.5) |
| 20 (58.8) |
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III + IV | 56 | 30 (53.5) | 0.092 | 18 (32.1) | 0.066 | 25 (44.6) | 0.021 | 43 (76.7) | 0.071 |
脉管癌栓: |
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阳性 | 23 | 10 (43.4) |
| 5 (21.7) |
| 10 (43.3) |
| 16 (69.5) |
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阴性 | 67 | 32 (47.7) | 0.722 | 18 (26.8) | 0.627 | 22 (32.8) | 0.358 | 47 (70.1) | 0.958 |
神经浸润: |
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阳性 | 21 | 10 (47.6) |
| 9 (42.8) |
| 8 (38.0) |
| 17 (80.9) |
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阴性 | 69 | 32 (46.3) | 0.920 | 14 (20.2) | 0.038 | 24 (34.7) | 0.781 | 46 (66.2) | 0.211 |
肿瘤部位: |
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胃窦 | 54 | 28 (51.8) |
| 15 (27.7) |
| 21 (38.8) |
| 36 (66.6) |
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胃体 + 胃底 | 36 | 14 (38.8) | 0.227 | 8 (22.2) | 0.554 | 11 (30.5) | 0.418 | 27 (75.0) | 0.398 |
化疗疗效: |
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CR + PR + SD | 67 | 26 (38.8) |
| 17 (25.3) |
| 25 (37.3) |
| 44 (65.6) |
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PD | 23 | 16 (69.5) | 0.011 | 6 (26.0) | 0.946 | 7 (30.4) | 0.552 | 19 (82.6) | 0.126 |
病理反应: |
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pCR | 7 | 5 (71.4) |
| 1 (14.2) |
| 2 (28.5) |
| 6 (85.7) |
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Non-pCR | 83 | 37 (44.5) | 0.245 | 22 (26.5) | 0.794 | 30 (36.1) | 1.000 | 57 (68.6) | 0.670 |