代谢动力学参数 | 符号 | 原始参数值 |
胃排空速率(Gastric emptying rate) | GEC | 3.5 (L/h/kg−0.25) |
小肠吸收率(Intestinal absorptivity) | KoralC | 2.1 (L/h/kg−0.25) |
肝脏葡萄糖醛酸化(Glu in liver) | VmaxL_gluC | 9043 nmol/min/mg of protein |
KmL_glu | 45,800 nmol | |
小肠葡萄糖醛酸化(Glu in gut) | VmaxG_gluC | 361 nmol/min/mg of protein |
KmG_glu | 58,400 nmol | |
肝脏硫酸化(Sul in liver) | VmaxL_sulC | 149 nmol/h/g liver |
KmL_sul | 10,100 nmol | |
小肠上皮细胞体积(Enterocytes volume) | enterocytes | 0.122 (L) |
尿液排泄率(Urine excretion rate) | ||
BPA | KurineC | 0.06 (1/h/kg bw 0.75) |
BPAG | KurinebpagC | 0.35 (1/h/kg bw 0.75) |
BPAS | KurinebpasC | 0.03 (1/h/kg bw 0.75) |