代谢动力学参数

符号

原始参数值

胃排空速率(Gastric emptying rate)

GEC

3.5 (L/h/kg0.25)

小肠吸收率(Intestinal absorptivity)

KoralC

2.1 (L/h/kg−0.25)

肝脏葡萄糖醛酸化(Glu in liver)

VmaxL_gluC

9043 nmol/min/mg of protein

KmL_glu

45,800 nmol

小肠葡萄糖醛酸化(Glu in gut)

VmaxG_gluC

361 nmol/min/mg of protein

KmG_glu

58,400 nmol

肝脏硫酸化(Sul in liver)

VmaxL_sulC

149 nmol/h/g liver

KmL_sul

10,100 nmol

小肠上皮细胞体积(Enterocytes volume)

enterocytes

0.122 (L)

尿液排泄率(Urine excretion rate)

BPA

KurineC

0.06 (1/h/kg bw 0.75)

BPAG

KurinebpagC

0.35 (1/h/kg bw 0.75)

BPAS

KurinebpasC

0.03 (1/h/kg bw 0.75)