治疗组别 Treatment

肿瘤体积(14天) TV at day 14

肿瘤抑制(%) T/Cb (%)

p值

p value

Vehicle

2201.09 ± 68.01

--

--

Cisplatin顺铂(5 mg/kg)

637.79 ± 62.87

28.9

<0.0001

Pamica-1 (200 µg，即时给药，滴鼻)

1331.51 ± 139.21

60.4

<0.0001

Pamica-1 (200 µg，滴鼻)

1163.83 ± 52.88

52.8

<0.0001

Pamica-1 (150 µg，滴鼻)

1839.36 ± 83.57

83.5

0.0667

Pamica-1 (200 µg，肌肉注射)

929.69 ± 109.95

41.7

<0.0001

Pamica-1 + 顺铂(200 µg + 5 mg/kg，滴鼻 + I.V)

799.63 ± 82.86

36.3

<0.0001