临床病理学特征 | Nek6表达情况(n = 47) | 上调比例(%) | Χ2值 | P值 | 显著性 | |
上调(n = 31) | 下调/无显著变化(n = 16) | |||||
性别 |
|
|
| 0.506 | 0.477 |
|
男性 | 16 | 10 | 16/26 (61.5) |
|
| 不显著 |
女性 | 15 | 6 | 15/21 (71.4) |
|
| |
年龄 |
|
|
| 1.935 | 0.164 |
|
≥60 y | 19 | 13 | 19/32 (59.4) |
|
| 不显著 |
<60 y | 12 | 3 | 12/15 (80.0) |
|
| |
肿瘤大小 |
|
|
| 0.092 | 0.761 |
|
≥5 cm | 7 | 3 | 7/10 (70.0) |
|
| 不显著 |
<5 cm | 24 | 13 | 24/37 (64.9) |
|
| |
肿瘤数量 |
|
|
| 0.088 | 0.766 |
|
单个 | 28 | 14 | 28/42 (66.7) |
|
| 不显著 |
多个 | 3 | 2 | 3/5 (60.0) |
|
| |
血清AFP水平 |
|
|
| 0.587 | 0.444 |
|
≥ 400 ng/ml | 22 | 13 | 22/35 (62.9) |
|
| 不显著 |
<400 ng/ml | 9 | 3 | 9/12 (75.0) |
|
| |
HBsAg |
|
|
| 2.294 | 0.130 |
|
阴性 | 4 | 5 | 4/9 (44.4) |
|
| 不显著 |
阳性 | 27 | 11 | 27/38 (71.1) |
|
| |
Edmondson分级 |
|
|
| 8.081 | 0.005 |
|
I + II级 | 8 | 11 | 8/19 (42.1) |
|
| 显著 |
III级 | 23 | 5 | 23/28 (82.1) |
|
| |
纤维包膜 |
|
|
| 6.013 | 0.014 |
|
有 | 23 | 6 | 23/29 (79.3) |
|
| 显著 |
无 | 8 | 10 | 8/18 (44.4) |
|
|