| Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
| Age | 1064 |
|
|
|
|
| ≤60 | 588 | Reference |
|
|
|
| >60 | 476 | 2.036 (1.468~2.822) | <0.001 | 3.628 (2.186~6.019) | <0.001 |
| T stage | 1061 |
|
|
|
|
| T1 & T2 | 889 | Reference |
|
|
|
| T3 & T4 | 172 | 1.673 (1.152~2.429) | 0.007 | 2.186 (1.129~4.232) | 0.020 |
| N stage | 1045 |
|
|
|
|
| N0 | 507 | Reference |
|
|
|
| N1 & N2 & N3 | 538 | 2.145 (1.497~3.073) | <0.001 | 1.389 (0.743~2.595) | 0.303 |
| M stage | 909 |
|
|
|
|
| M0 | 889 | Reference |
|
|
|
| M1 | 20 | 4.327 (2.508~7.465) | <0.001 | 3.040 (1.212~7.624) | 0.018 |
| Pathologic stage | 1041 |
|
|
|
|
| Stage I & Stage II | 785 | Reference |
|
|
|
| Stage III & Stage IV | 256 | 2.519 (1.787~3.549) | <0.001 | 2.096 (1.002~4.384) | 0.049 |
| ER status | 1014 |
|
|
|
|
| Negative | 237 | Reference |
|
|
|
| Positive | 777 | 0.704 (0.487~1.017) | 0.062 | 0.463 (0.275~0.779) | 0.004 |
| PR status | 1011 |
|
|
|
|
| Negative | 338 | Reference |
|
|
|
| Positive | 673 | 0.762 (0.541~1.074) | 0.120 |
|
|
| HER2 status | 705 |
|
|
|
|
| Negative | 548 | Reference |
|
|
|
| Positive | 157 | 1.611 (0.981~2.644) | 0.059 | 0.880 (0.493~1.569) | 0.665 |
| GGCT | 1064 |
|
|
|
|
| Low | 533 | Reference |
|
|
|
| High | 531 | 1.664 (1.194~2.320) | 0.003 | 1.856 (1.123~3.069) | 0.016 |