|
| |||||
| Entry | Pd/L | Solvent | T (℃) | T (min) | Yield (%)b |
| 1 | Pd(PPh3)4 | PhMe | rt | 50 | 76 |
| 2 | Pd(PPh3)4 | DME | rt | 50 | 69 |
| 3 | Pd(PPh3)4 | THF | rt | 4 | 58 |
| 4 | Pd(PPh3)4 | MeCN | rt | 35 | 60 |
| 5 | Pd(PPh3)4 | DCM | rt | 8 | 88 |
| 6 | Pd(PPh3)4 | DMSO | rt | 30 | 57 |
| 7 | Pd(PPh3)4 | H2O | rt | 10 | 47 |
| 8 | Pd(dba)2 | DCM | rt | 20 | 65 |
| 9 | Pd(dppf)Cl2 | DCM | rt | 28 | 70 |
| 10 | Pd(OAc)2 | DCM | rt | 16 | 46 |
| 11c | PdCl2/PPh3 | DCM | rt | 20 | 75 |
| 12d | Pd(dba)2/PPh3 | DCM | rt | 20 | 77 |
| 13 | Pd(PPh3)Cl2 | DCM | rt | 30 | 73 |
| 14 | Pd(PPh3)4 | DCM | 40 | 8 | 85 |
| 15 | Pd(PPh3)4 | DCM | 80 | 8 | 80 |
| 16 | Pd(PPh3)4 | DCM | 0 | 45 | 60 |
