| Variables |
| Before PSM |
|
| After PSM |
|
| All patients | Survival time (months) median (95% CI) | P value | All patients | Survival time (months) median (95% CI) | P value | |
| Group |
|
| 0.002 |
|
| 0.053 |
| F0~4 | 166 | 82 (67.731~96.269) |
| 164 | 82 (66.397~97.603) |
|
| F5~6 | 1370 | 69 (65.284~72.716) |
| 164 | 66 (57.970~74.030) |
|
| Age |
|
| <0.001 |
|
| 0.044 |
| ≤60 | 973 | 79 (74.673~83.327) |
| 196 | 82 (64.906~99.094) |
|
| >60 | 563 | 56 (49.586~62.414) |
| 132 | 61 (50.962~71.038) |
|
| Sex |
|
| 0.002 |
|
| 0.364 |
| Male | 1205 | 72 (67.500~76.500) |
| 265 | 78 (64.530–91.470) |
|
| Female | 331 | 60 (52.152~67.848) |
| 63 | 68 (58.857–77.143) |
|
| AJCC T, 7th ed. |
|
| <0.001 |
|
| <0.001 |
| T1~T2 | 765 | 46 (43.166~48.834) |
| 155 | 47 (41.926~52.074) |
|
| T3~T4 | 35 | 54 (44.367~63.633) |
| 8 | 60 (47.118~72.882) |
|
| Unclear | 736 | 110 (107.186~112.814) | <0.001 | 165 | 116 (109.500~122.500) | <0.001 |
| AJCC N, 7th ed. |
|
|
|
|
|
|
| N0 | 791 | 46 (43.331~48.669) |
| 157 | / |
|
| N1 | 5 | / |
| 2 | / |
|
| Unclear. | 740 | 110 (107.180~112.820) | <0.001 | 169 | / | <0.001 |
| AJCC M, 7th ed |
|
|
|
|
|
|
| M0 | 796 | 46 (43.290~48.710) |
| 163 | 48 (43.079~52.921) |
|
| M1 | 6 | 46 (7.079~84.921) |
| 0 | / |
|
| Unclear | 734 | 110 (107.187~112.813) |
| 165 | 116 (109.500~122.500) |
|
| Grade, n |
|
| 0.006 |
|
| 0.031 |
| Well differentiated; Grade I | 383 | 72 (64.428~79.572) |
| 92 | / |
|
| Moderately differentiated; Grade II | 578 | 68 (62.454~73.546) |
| 120 | / |
|
| Poorly differentiated; Grade III | 115 | 91 (76.867~105.133) |
| 29 | / |
|
| Undifferentiated; anaplastic; Grade IV | 7 | 57 |
| 2 | / |
|
| Unknown | 453 | 66 (60.917~71.083) |
| 85 | / |
|
| AFP |
|
| 0.086 |
|
| 0.138 |
| Positive/elevated | 758 | 70 (66.041~73.959) |
| 167 | 70 (59.038~80.962) |
|
| Negative | 508 | 67 (60.709~73.291) |
| 105 | 71 (58.040~83.960) |
|
| Unclear | 270 | 81 (64.346~97.654) |
| 56 | 90 (60.854~119.146) |
|
| Tumor size |
|
| <0.001 |
|
| <0.001 |
| ≤1 cm | 1421 | 74 (70.434~77.566) |
| 304 | 79 (66.871~91.129) |
|
| >1 cm | 3 | / |
| 2 | / |
|
| Unclear | 112 | / |
| 22 | / |
|
| Race (White, Black, Other) |
|
| 0.005 |
|
| 0.007 |
| White | 1183 | 70 (65.701~74.299) |
| 228 | 69 (59.566~78.434) |
|
| Black | 130 | 56 (44.243~67.757) |
| 36 | 64 (38.543~89.457) |
|
| Other | 215 | 80 (67.866~92.134) |
| 64 | 110 (98.320~121.680) |
|
| Lymph involvement, n |
|
| <0.001 |
|
| <0.001 |
| No | 1417 | 74 (70.393~77.607) |
| 301 | / |
|
| Yes | 10 | 79 (35.880~122.120) |
| 2 | / |
|
| Unclear | 109 | 7 (5.967~8.033) |
| 25 | / |
|
| Distant metastasis, n |
|
| <0.001 |
|
|
|
| No | 1426 | 74 (70.424~77.576) |
| 306 | / | <0.001 |
| Yes | 8 | 71 (18.836~123.164) |
| 1 | / |
|
| Unclear | 102 | 7 (5.998~8.002) |
| 21 | / |
|