因素

non-HF组(N = 103)

HF组(N = 103)

P值

性别(男/女)

49/54

64/39

0.069

年龄(岁)

68.17 ± 5.58

70.39 ± 10.66

0.063

BMI (kg/m²)

23.60 ± 3.52

24.35 ± 3.74

0.141

MAP (mmHg)

90.28 ± 9.54

92.58 ± 11.88

0.126

总胆固醇(mmol/L)

4.79 ± 1.00

3.69 ± 1.03^*

0.000

甘油三酯(mmol/L)

1.26 (0.96, 1.90)

0.91 (0.74, 1.31)^*

0.000

HDL-C (mmol/L)

1.18 ± 0.27

0.97 ± 0.25^*

0.000

LDL-C (mmol/L)

2.79 ± 0.69

2.18 ± 0.74^*

0.000

载脂蛋白A1 (g/L)

1.35 ± 0.20

1.08 ± 0.24^*

0.000

载脂蛋白B (g/L)

0.97 ± 0.24

0.84 ± 0.34^*

0.001

ALT (U/L)

14.74 (11.93, 22.3)

18.09 (15.37, 20.45)

0.717

AST (U/L)

14.81 (10.23, 27.00)

20.87 (16.91, 26.35)^*

0.000

肌酐(mmol/L)

66.42 ± 11.98

82.07 ± 18.17^*

0.000

尿素氮(mmol/L)

6.58 ± 1.81

7.07 ± 2.32

0.069

空腹血糖(mmol/L)

5.24 ± 0.98

6.24 ± 2.07^*

0.000

糖化血红蛋白(%)

5.82 ± 1.36

6.57 ± 1.48^*

0.000

NT-ProBNP (ng/L)

63.87 (30, 102.5)

1239.16 (518, 3535)^*

0.000

室间隔厚度(mm)

8.54 ± 1.11

9.53 ± 1.58^*

0.000

左室后壁厚度(mm)

8.46 ± 1.07

9.17 ± 1.1^*

0.000

左房内径(mm)

34.49 ± 3.87

44.48 ± 7.72^*

0.000

LVEDD (mm)

45.21 ± 3.90

52.55 ± 8.63^*

0.000

E/A

0.99 ± 0.34

1.15 ± 0.71

0.058

E/e¢

8 (7, 10)

13 (11, 18)^*

0.000

LVEF (%)

61.09 ± 2.51

43.5 ± 13.35^*

0.000

糖尿病患病率

12 (11.7%)

42 (40.8%)^*

0.036

高血压患病率

35 (34%)

83 (80.6%)^*

0.000

冠心病患病率

6 (5.8%)

86 (83.5%)^*

0.000

达格列净

7 (6.8%)

29 (28.2%)^*

0.000

抗血小板类

6 (5.8%)

43 (41.7%)^*

0.000

他汀类

28 (27.2%)

82 (79.6%)^*

0.000

ACEI/ARB/ARNI

20 (19.4%)

74 (71.8%)^*

0.000

β受体阻滞剂

13 (12.6%)

82 (79.6%)^*

0.000

钙离子阻滞剂

11 (0.7%)

26 (25.2%)^*

0.006

利尿剂

2 (1.9%)

93 (90.3%)^*

0.000

硝酸酯类

1 (1%)

35 (34%)^*

0.000

SGK1 (ng/mL)

0.24 (0.19, 0.29)

0.32 (0.20, 0.52)^*

0.000