SNPs | 染色体 | 位置 | 有效等位基因 | T2DM | 衰弱 | F统计量 | ||||
其他等位基因 | β | SE | P | β | SE | P | ||||
rs10195252 | 2 | 165513091 | C/T | −0.0035322 | 0.00045299 | 6.30E−15 | −0.004 | 0.0034 | 0.2306 | 60.8024755 |
rs10421566 | 19 | 46159123 | T/C | 0.00377769 | 0.00049403 | 2.10E−14 | 0.0033 | 0.0037 | 0.3715 | 58.4726829 |
rs1064173 | 6 | 32627480 | A/G | 0.00834518 | 0.00051552 | 6.10E−59 | 0.0144 | 0.0038 | 0.0001609 | 262.0467 |
rs10811660 | 9 | 22134068 | A/G | −0.0071013 | 0.00058755 | 1.20E−33 | −0.0053 | 0.0044 | 0.2278 | 146.07775 |
rs10830963 | 11 | 92708710 | G/C | 0.00478562 | 0.00049727 | 6.30E−22 | 0.0017 | 0.0037 | 0.6423 | 92.6165095 |
rs10974438 | 9 | 4291928 | C/A | 0.00280019 | 0.00046601 | 1.90E−09 | −0.0044 | 0.0035 | 0.2029 | 36.1059633 |
rs11257655 | 10 | 12307894 | T/C | 0.00422685 | 0.00054714 | 1.10E−14 | 0.0075 | 0.0041 | 0.0642303 | 59.6813073 |
rs112674299 | 3 | 63982670 | T/C | −0.0037258 | 0.00065403 | 1.20E−08 | −0.0141 | 0.0049 | 0.00386901 | 32.4511751 |
rs114355928 | 6 | 32265881 | T/G | 0.0110325 | 0.0013364 | 1.50E−16 | 0.0492 | 0.0099 | 5.87E−07 | 68.1514246 |
rs11658063 | 17 | 36103872 | G/C | −0.0038931 | 0.00045816 | 1.90E−17 | −0.0016 | 0.0034 | 0.6369 | 72.2034226 |
rs1169299 | 12 | 121429194 | C/T | 0.00265339 | 0.00044735 | 3.00E−09 | 0.0064 | 0.0033 | 0.0524397 | 35.1812427 |
rs11712037 | 3 | 12344730 | G/C | −0.0045367 | 0.00068705 | 4.00E−11 | 0.0071 | 0.0051 | 0.1639 | 43.6014438 |
rs11720108 | 3 | 123069058 | T/C | −0.0040812 | 0.00051621 | 2.70E−15 | −0.0015 | 0.0038 | 0.7038 | 62.5050147 |
rs11759026 | 6 | 126792095 | G/A | 0.00393527 | 0.0005316 | 1.30E−13 | −0.0114 | 0.004 | 0.00395503 | 54.80085 |
rs1182395 | 7 | 157032924 | G/T | 0.00281587 | 0.00046713 | 1.70E−09 | 0.0028 | 0.0035 | 0.4156 | 36.3378293 |
rs1215468 | 13 | 80707429 | G/A | −0.0041615 | 0.0004918 | 2.60E−17 | 0.0048 | 0.0037 | 0.1927 | 71.6037478 |
rs1260326 | 2 | 27730940 | C/T | 0.0036418 | 0.00045401 | 1.00E−15 | −0.0052 | 0.0034 | 0.123 | 64.3435728 |
rs12910361 | 15 | 77782335 | G/A | 0.00354186 | 0.00049084 | 5.40E−13 | 0.0039 | 0.0037 | 0.2895 | 52.0702862 |
rs13116313 | 4 | 96121988 | G/A | −0.002755 | 0.0004997 | 3.50E−08 | −0.006 | 0.0037 | 0.1064 | 30.3970289 |
rs1320164 | 8 | 95960767 | A/G | −0.0026447 | 0.00044473 | 2.70E−09 | −0.0043 | 0.0033 | 0.1895 | 35.3644711 |
rs13262861 | 8 | 41508577 | A/C | −0.0044371 | 0.00059253 | 7.00E−14 | −0.002 | 0.0044 | 0.646399 | 56.0767241 |
rs1333045 | 9 | 22119195 | C/T | 0.00249961 | 0.00044558 | 2.00E−08 | 0.0109 | 0.0033 | 0.00096701 | 31.4691731 |
rs13414381 | 2 | 43567218 | C/T | −0.0053685 | 0.00066711 | 8.50E−16 | 0.0074 | 0.005 | 0.134 | 64.7606694 |
rs1496653 | 3 | 23454790 | G/A | −0.003955 | 0.00055162 | 7.50E−13 | 0.0022 | 0.0041 | 0.597301 | 51.4044875 |
rs17168486 | 7 | 14898282 | T/C | 0.00322875 | 0.00058983 | 4.40E−08 | 0.0025 | 0.0044 | 0.5645 | 29.9652612 |
rs17753004 | 20 | 62445068 | A/G | −0.0031065 | 0.00052413 | 3.10E−09 | −0.0143 | 0.0039 | 0.0002616 | 35.1277376 |
rs1783541 | 11 | 65294799 | T/C | 0.00301673 | 0.00053932 | 2.20E−08 | 0.0086 | 0.004 | 0.03264 | 31.2886103 |
rs1800961 | 20 | 43042364 | T/C | 0.0087451 | 0.00128329 | 9.50E−12 | 0.0031 | 0.0093 | 0.736801 | 46.4386878 |
rs1810534 | 20 | 32437142 | T/C | 0.00272865 | 0.0004467 | 1.00E−09 | −9.00E−04 | 0.0033 | 0.791899 | 37.3131416 |
rs2183237 | 14 | 38803756 | A/G | −0.0028544 | 0.00051859 | 3.70E−08 | −0.0093 | 0.0039 | 0.01583 | 30.2962905 |
rs2237895 | 11 | 2857194 | C/A | 0.00435582 | 0.00045028 | 3.90E−22 | −0.0022 | 0.0033 | 0.5189 | 93.5785827 |
rs2258238 | 12 | 66221060 | T/A | 0.00528048 | 0.00072204 | 2.60E−13 | 5.00E−04 | 0.0054 | 0.925 | 53.4844948 |
rs2303700 | 19 | 7976529 | C/T | −0.0029377 | 0.0004822 | 1.10E−09 | −0.0037 | 0.0036 | 0.3069 | 37.1166002 |
rs231361 | 11 | 2691500 | A/G | 0.00368685 | 0.0005137 | 7.10E−13 | 0.0042 | 0.0038 | 0.2695 | 51.5110331 |
rs2793829 | 1 | 120461253 | T/C | 0.00447507 | 0.00071823 | 4.60E−10 | 0.0038 | 0.0053 | 0.4767 | 38.8212 |
rs2796441 | 9 | 84308948 | A/G | −0.0034839 | 0.00044981 | 9.50E−15 | −0.0033 | 0.0033 | 0.3285 | 59.9892109 |
rs2972144 | 2 | 227101411 | G/A | 0.00386474 | 0.00046492 | 9.30E−17 | 0.0069 | 0.0035 | 0.0461105 | 69.1024503 |
rs301043 | 12 | 95887021 | G/A | 0.00260062 | 0.00047158 | 3.50E−08 | 0.0073 | 0.0035 | 0.0383504 | 30.4123799 |
rs3383 | 6 | 143073041 | C/T | 0.00279938 | 0.00046252 | 1.40E−09 | 0.0014 | 0.0034 | 0.6844 | 36.6316974 |
rs34715063 | 15 | 38873115 | C/T | 0.00472233 | 0.00066837 | 1.60E−12 | 0.0052 | 0.005 | 0.2988 | 49.9203325 |
rs34744311 | 10 | 94467287 | T/C | −0.0049677 | 0.0004594 | 3.00E−27 | −0.0031 | 0.0034 | 0.3679 | 116.934671 |
rs34872471 | 10 | 114754071 | C/T | 0.0146745 | 0.00048948 | 1.80E−197 | 0.0135 | 0.0036 | 0.0002216 | 898.775859 |
rs35612982 | 6 | 20682622 | C/T | 0.00694287 | 0.00058089 | 6.30E−33 | 0.0025 | 0.0043 | 0.5598 | 142.851821 |
rs3798519 | 6 | 50788778 | C/A | 0.00351907 | 0.00057883 | 1.20E−09 | −1.00E−04 | 0.0043 | 0.9741 | 36.9622372 |
rs3802177 | 8 | 118185025 | A/G | −0.0045101 | 0.00048148 | 7.40E−21 | 1.00E−04 | 0.0036 | 0.9835 | 87.7440187 |
rs429358 | 19 | 45411941 | C/T | −0.0033938 | 0.0006158 | 3.60E−08 | 0.0037 | 0.0046 | 0.4142 | 30.3744101 |
rs459193 | 5 | 55806751 | G/A | 0.00322651 | 0.00051003 | 2.50E−10 | 0.0091 | 0.0038 | 0.0169899 | 40.0197699 |
rs4660303 | 1 | 40060473 | A/G | 0.00352585 | 0.00053232 | 3.50E−11 | 0.0193 | 0.004 | 1.10E−06 | 43.8709665 |
rs4686471 | 3 | 187740899 | C/T | 0.00277132 | 0.00045772 | 1.40E−09 | 5.00E−04 | 0.0034 | 0.8866 | 36.6580854 |
rs4689394 | 4 | 6291003 | G/C | 0.00436989 | 0.00045469 | 7.20E−22 | 0.006 | 0.0034 | 0.0745899 | 92.3643702 |
rs4727554 | 7 | 102383690 | A/C | 0.00286534 | 0.00045518 | 3.10E−10 | 6.00E−04 | 0.0034 | 0.8631 | 39.6266985 |
rs5213 | 11 | 17408404 | T/C | −0.0034532 | 0.00046814 | 1.60E−13 | 0.003 | 0.0035 | 0.3867 | 54.4124385 |
rs58432198 | 1 | 51256091 | T/C | −0.003943 | 0.00069593 | 1.50E−08 | 0.0104 | 0.0052 | 0.0433002 | 32.1004724 |
rs6567160 | 18 | 57829135 | C/T | 0.00376256 | 0.00052601 | 8.50E−13 | 0.003 | 0.0039 | 0.4484 | 51.1656938 |
rs6679677 | 1 | 114303808 | A/C | 0.00429112 | 0.00073711 | 5.80E−09 | 0.0171 | 0.0055 | 0.001736 | 33.8905853 |
rs6885132 | 5 | 14768092 | G/C | −0.0048998 | 0.00075312 | 7.70E−11 | −0.01 | 0.0056 | 0.0759906 | 42.3271942 |
rs7174878 | 15 | 90434888 | G/A | −0.0033156 | 0.00050711 | 6.20E−11 | 0.0018 | 0.0038 | 0.630099 | 42.7477105 |
rs72802365 | 16 | 75246035 | C/G | −0.0062551 | 0.00083109 | 5.20E−14 | −0.0118 | 0.0062 | 0.0575904 | 56.6469117 |
rs74567345 | 5 | 102301358 | C/T | 0.00863228 | 0.00103112 | 5.70E−17 | −0.0122 | 0.0077 | 0.1101 | 70.0862166 |
rs7615045 | 3 | 185521126 | G/A | 0.00538022 | 0.00047828 | 2.30E−29 | 0.012 | 0.0036 | 0.0007936 | 126.540685 |
rs76895963 | 12 | 4384844 | G/T | −0.0205539 | 0.00172161 | 7.40E−33 | −2.00E−04 | 0.0128 | 0.9886 | 142.534148 |
rs77464186 | 11 | 72460398 | C/A | −0.0054715 | 0.00061258 | 4.20E−19 | 0.0042 | 0.0045 | 0.3487 | 79.7792311 |
rs7807512 | 7 | 130448914 | T/C | 0.00284072 | 0.00049051 | 7.00E−09 | 0.0029 | 0.0037 | 0.4277 | 33.5403978 |
rs79687284 | 1 | 214150821 | C/G | 0.00865526 | 0.00121422 | 1.00E−12 | 0.0116 | 0.0091 | 0.2014 | 50.8119044 |
rs860262 | 7 | 28194397 | A/C | −0.0040552 | 0.0004445 | 7.30E−20 | −0.0103 | 0.0033 | 0.001854 | 83.2306633 |
rs9271731 | 6 | 32593612 | G/A | 0.00559819 | 0.00056865 | 7.20E−23 | 0.0212 | 0.0042 | 4.34E−07 | 96.9171421 |
rs9379084 | 6 | 7231843 | A/G | −0.0058525 | 0.00071623 | 3.10E−16 | −0.0074 | 0.0054 | 0.1696 | 66.769808 |
rs9937354 | 16 | 53799847 | A/G | 0.00543965 | 0.00044979 | 1.10E−33 | 0.0043 | 0.0033 | 0.1936 | 146.260207 |