临床病理特征 | IDC组 (n = 1746) | ILC组 (n = 57) | 值 | P值 |
性别 |
|
|
|
|
男性 | 2 (0.1) | 0 (0.0) | — | 1.000 |
女性 | 1744 (99.9) | 57 (100.0) | ||
年龄(岁) | 52.41 ± 10.31 | 54.18 ± 9.36 | −1.279 | 0.201 |
BMI |
|
|
|
|
<24 | 1065 (61.0) | 37 (64.9) | 0.356 | 0.551 |
≥24 | 681 (39.0) | 20 (35.1) | ||
婚姻状况 |
|
|
|
|
已婚 | 1609 (92.2) | 55 (96.5) | 0.914 | 0.339 |
其他* | 137 (7.8) | 2 (3.5) | ||
月经状态# |
|
|
|
|
绝经前 | 913 (52.3) | 24 (42.1) | 2.321 | 0.128 |
绝经后 | 831 (47.6) | 33 (57.9) | ||
生育史 |
|
|
|
|
有 | 1608 (92.1) | 56 (98.2) | 2.133 | 0.144 |
无 | 138 (7.9) | 1 (1.8) | ||
乳腺癌家族史 |
|
|
|
|
有 | 20 (1.1) | 0 (0.0) | — | 1.000 |
无 | 1726 (98.9) | 57 (100.0) | ||
系统疾病 |
|
|
|
|
有 | 454 (26.0) | 16 (28.1) | 0.122 | 0.726 |
无 | 1292 (74.0) | 41 (71.9) | ||
乳房手术方式 |
|
|
|
|
单切 | 1462 (83.7) | 47 (82.5) | 0.066 | 0.797 |
保乳 | 284 (16.3) | 10 (17.5) | ||
腋窝手术方式 |
|
|
|
|
SLNB | 779 (44.6) | 29 (50.9) | 0.875 | 0.350 |
ALND | 967 (55.4) | 28 (49.1) | ||
病理肿瘤大小 |
|
|
|
|
T1 | 1088 (62.3) | 36 (63.2) | 1.699 | 0.428 |
T2 | 613 (35.1) | 18 (31.6) | ||
T3-4 | 45 (2.6) | 3 (5.3) | ||
淋巴结转移 |
|
|
|
|
有 | 599 (34.3) | 17 (29.8) | 0.493 | 0.483 |
无 | 1147 (65.7) | 40 (70.2) | ||
LVI |
|
|
|
|
有 | 171 (9.8) | 3 (5.3) | 1.299 | 0.254 |
无 | 1575 (90.2) | 54 (94.7) | ||
ER状态 |
|
|
|
|
阴性 | 463 (26.5) | 6 (10.5) | 7.334 | 0.007 |
阳性 | 1283 (73.5) | 51 (89.5) | ||
PR状态 |
|
|
|
|
阴性 | 732 (41.9) | 16 (28.1) | 4.364 | 0.037 |
阳性 | 1014 (58.1) | 41 (71.9) | ||
HER-2状态 |
|
|
|
|
阴性 | 1128 (64.6) | 47 (82.5) | 7.951 | 0.019 |
阳性 | 428 (24.5) | 6 (10.5) | ||
未知 | 190 (10.9) | 4 (7.0) | ||
Ki-67指数 |
|
|
|
|
<14% | 544 (31.2) | 29 (50.9) | 11.203 | 0.004 |
≥14% | 1112 (63.7) | 24 (42.1) | ||
未知 | 90 (5.2) | 4 (7.0) | ||
分子分型 |
|
|
|
|
Luminal A型 | 318 (18.2) | 16 (28.1) | 12.209 | 0.032 |
Luminal B型(HER-2阴性) | 587 (33.6) | 26 (45.6) | ||
Luminal B型(HER-2阳性) | 149 (8.5) | 5 (8.8) | ||
HER2阳性型 | 172 (9.9) | 2 (3.5) | ||
三阴性 | 261 (14.9) | 4 (7.0) | ||
未知 | 259 (14.8) | 4 (7.0) |