| 变量 | HR (95% CI) | P值 | |
| 主要治疗结果 |
|
| |
| 完全缓解 | 1.0 [Reference] |
| |
| 部分缓解 | 1.53 (0.62~3.79) | 0.359 | |
| 病情稳定 | 2.91 (1.43~5.89) | <0.001 | |
| 疾病进展 | 13 (6.81~24.83) | 0.003 | |
| 术后 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 0.73 (0.46~1.14) | 0.168 | |
| 放射治疗 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 0.76 (0.47~1.21) | 0.243 | |
| 组织学类型 |
|
| |
| 星形细胞瘤 | 1.0 [Reference] |
| |
| 少星形细胞瘤 | 0.04 (0~1.45) | 0.078 | |
| 少突胶质细胞瘤 | 0.03 (0~1.86) | 0.096 | |
| 性别 |
|
| |
| 女 | 1.0 [Reference] |
| |
| 男 | 0.87 (0.61~1.24) | 0.446 | |
| ICD-O-3 组织学编码 |
|
| |
| 9382/3 | 1.0 [Reference] |
| |
| 9400/3 | 0.03 (0~1.15) | 0.059 | |
| 9401/3 | 0.09 (0~4.01) | 0.217 | |
| 9450/3 | 1.03 (0.16~6.63) | 0.976 | |
| 9451/3 | 0.9 (0.12~6.92) | 0.920 | |
| 年龄(岁) |
|
| |
| ≤40 | 1.0 [Reference] |
| |
| >40 | 1.96 (1.35~2.86) | <0.001 | |
| 肿瘤组织学分级 |
|
| |
| G2 | 1.0 [Reference] |
| |
| G3 | 1 (0.45~2.27) | 0.991 | |
| 癫痫发作史 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 1.01 (0.64~1.62) | 0.952 | |
| 头痛史 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 1.5 (0.96~2.35) | 0.075 | |
| 精神状态改变史 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 0.86 (0.53~1.39) | 0.534 | |
| 运动改变史 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 0.96 (0.56~1.64) | 0.885 | |
| 首次症状持续时间(天) |
|
| |
| >180 | 1.0 [Reference] |
| |
| 0~30 | 2.56 (1.51~4.35) | <0.001 | |
| 31~90 | 2.16 (1.19~3.93) | 0.012 | |
| 91~180 | 2.64 (1.12~6.2) | 0.026 | |
| IDH1突变测试 |
|
| |
| 否 | 1.0 [Reference] |
| |
| 是 | 1.01 (0.67~1.53) | 0.967 | |