Caco-2

CYP3A4

hERG

HOB

MN

1

0

0

0

1

1

1

1

1

1

0

0

0

1

1

1

2

0

0

0

1

1

1

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1

1

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0

1

1

1

3

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1

1

1

1

1

1

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1

1

1

4

0

0

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1

1

1

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1

1

0

0

0

1

1

1

5

0

0

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1

1

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1

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0

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1

1

1

6

0

0

0

1

1

1

1

1

1

0

0

0

1

1

1

7

0

0

0

1

1

1

1

1

1

0

0

0

1

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1

8

0

0

0

1

1

1

1

1

1

0

0

0

1

1

1

9

0

0

0

1

1

1

1

0

1

0

0

0

1

1

1

10

0

0

0

1

1

1

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1

1

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1

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11

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12

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13

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15

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1

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18

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20

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21

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1

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22

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23

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24

1

1

1

1

1

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1

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0

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1

0

0

0

25

1

1

1

0

0

0

1

1

1

0

0

1

1

1

0

26

1

1

1

0

0

0

1

1

1

0

0

1

1

1

0

27

0

1

0

1

1

1

1

1

1

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0

0

0

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28

0

0

0

1

1

1

1

1

1

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0

0

1

1

1

29

0

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1

1

1

1

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1

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1

1

1

30

0

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1

1

1

1

1

1

1

1

1

1

1

1

31

0

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1

1

1

1

1

1

1

1

1

1

1

1

32

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1

1

1

1

1

1

1

1

1

1

1

1

33

1

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1

1

1

1

1

1

1

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1

1

1

34

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1

1

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1

1

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1

35

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1

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1

1

1

1

1

1

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0

1

1

1

36

0

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1

1

1

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1

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0

1

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1

1

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37

0

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1

1

1

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1

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0

1

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1

1

1

38

0

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1

1

1

1

1

1

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0

0

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39

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1

1

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1

1

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1

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1

1

1

40

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1

1

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1

1

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1

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1

1

1

41

0

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1

1

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1

1

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1

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1

1

1

42

0

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1

1

1

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1

1

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1

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1

1

1

43

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1

1

1

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1

1

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1

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1

1

1

44

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1

1

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1

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45

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46

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1

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47

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48

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1

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1

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1

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1

49

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1

1

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1

1

1

0

1

0

1

1

1

50

0

1

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1

1

1

1

1

1

0

0

0

0

0

0