变量 | 总体(n = 309) | 非ROP组(n = 200) | ROP组(n = 109) | P值 |
产妇资料 | ||||
高龄产妇,n (%) | 117 (38) | 76 (38) | 41 (38) | 1 |
产前感染,n (%) | 105 (34) | 58 (29) | 47 (43) | 0.017 |
妊娠期高血压,n (%) | 121 (39) | 85 (42) | 36 (33) | 0.132 |
妊娠期糖尿病,n (%) | 51 (17) | 38 (19) | 13 (12) | 0.15 |
孕次,M (Q1, Q3) | 2 (1, 3) | 2 (2, 3) | 2 (1, 3) | 0.062 |
产次,M (Q1,Q3) | 2 (1, 2) | 2 (1, 2) | 2 (1, 2) | 0.058 |
顺产,n (%) | 101 (33) | 51 (26) | 50 (46) | <0.001 |
产前激素使用次数,M (Q1, Q3) | 2 (1, 4) | 2 (1, 4) | 2 (0, 4) | 0.303 |
新生儿资料 | ||||
出生胎龄,周,Mean ± SD | 28.46 ± 1.58 | 28.92 ± 1.45 | 27.63 ± 1.46 | <0.001 |
出生体重,g,M (Q1, Q3) | 980 (890, 1100) | 990 (917.5, 1200) | 910 (850, 990) | <0.001 |
生后体重增加,g/天,M (Q1, Q3) | 15.65 (11.3, 20.43) | 17.61 (13.48, 22.17) | 12.61 (9.57, 16.52) | <0.001 |
恢复出生体重时间,M (Q1, Q3) | 10 (7, 13) | 9 (7, 12) | 10 (8, 14) | 0.013 |
多胎,n (%) | 74 (24) | 41 (20) | 33 (30) | 0.074 |
男性,n (%) | 165 (53) | 107 (54) | 58 (53) | 1 |
PDA, n (%) | 159 (51) | 94 (47) | 65 (60) | 0.045 |
RDS, n (%) | 259 (84) | 164 (82) | 95 (87) | 0.31 |
PPHN, n (%) | 44 (14) | 24 (12) | 20 (18) | 0.175 |
BIPI, n (%) | 58 (19) | 32 (16) | 26 (24) | 0.124 |
PNAC, n (%) | 74 (24) | 45 (22) | 29 (27) | 0.504 |
肺炎,n (%) | 206 (67) | 132 (66) | 74 (68) | 0.833 |
败血症,n (%) | 93 (30) | 58 (29) | 35 (32) | 0.66 |
甲状腺功能减低,n (%) | 115 (37) | 65 (32) | 50 (46) | 0.028 |
NEC, n (%) | 32 (10) | 21 (10) | 11 (10) | 1 |
生后窒息,n (%) | 199 (64) | 117 (58) | 82 (75) | 0.005 |
出生贫血,n (%) | 64 (21) | 39 (20) | 25 (23) | 0.572 |
BPD, n (%) | 276 (89) | 174 (87) | 102 (94) | 0.11 |
机械通气,n (%) | 104 (34) | 51 (26) | 53 (49) | <0.001 |
无创呼吸机 ≥ 2周,n (%) | 252 (82) | 150 (75) | 102 (94) | <0.001 |
吸氧 ≥ 2周,n (%) | 202 (65) | 112 (56) | 90 (83) | <0.001 |
FiO2 ≥ 0.3使用24 h以上,n (%) | 156 (50) | 86 (43) | 70 (64) | <0.001 |
钙磷补充,n (%) | 196 (63) | 125 (62) | 71 (65) | 0.737 |
输血次数 ≥ 3次,n (%) | 171 (55) | 79 (40) | 92 (84) | <0.001 |
PS治疗,n (%) | 160 (52) | 99 (50) | 61 (56) | 0.333 |
激素治疗,n (%) | 78 (25) | 37 (18) | 41 (38) | <0.001 |
利尿剂治疗,n (%) | 95 (31) | 57 (28) | 38 (35) | 0.303 |
肠外营养天数,M (Q1, Q3) | 28 (19, 41) | 26 (18, 37.25) | 32 (20, 50) | <0.001 |
肠内喂养开始时间,M (Q1, Q3) | 1 (0, 2) | 1 (0, 2) | 1 (0, 2) | 0.127 |
禁食天数,M (Q1, Q3) | 1 (0, 3) | 1 (0, 3.25) | 1 (0, 3) | 0.598 |
咖啡因使用天数,M (Q1, Q3) | 45 (33, 59) | 43 (31, 53) | 54 (41, 67) | <0.001 |