序号 | 基因 | SNP | 基因型 | 病例[n(%)] | 对照[n(%)] | OR | 95% CI | P值 |
1 | miR-34b/c | rs4938723 | TT | 70 (29.9) | 81 (34.6) | 1.000 (Ref.) | ||
TC | 105 (44.9) | 113 (48.3) | 1.075 | 0.709~1.630 | 0.732 | |||
CC | 59 (25.2) | 40 (17.1) | 1.707 | 1.022~2.852 | 0.041 | |||
2 | KIF1B | rs17401966 | AA | 111 (47.4) | 101 (43.2) | 1.000 (Ref.) | ||
AG | 95 (40.6) | 86 (36.8) | 1.005 | 0.676~1.495 | 0.98 | |||
GG | 28 (12.0) | 47 (20.0) | 0.542 | 0.316~0.930 | 0.026 | |||
3 | EFCAB11 | rs12100561 | AA | 86 (36.7) | 77 (32.9) | 1.000 (Ref.) | ||
AG | 57 (24.4) | 46 (19.7) | 1.109 | 0.676~1.821 | 0.681 | |||
GG | 91 (38.9) | 111 (47.4) | 0.734 | 0.485~1.110 | 0.143 | |||
4 | BACH2 | rs10944479 | AA | 64 (27.4) | 68 (29.1) | 1.000 (Ref.) | ||
AC | 86 (36.7) | 91 (38.9) | 0.84 | 0.529~1.334 | 0.461 | |||
CC | 84 (35.9) | 75 (32.0) | 0.844 | 0.550~1.296 | 0.438 | |||
5 | HLA-DRB1 | rs2647073 | AA | 91 (38.9) | 76 (32.5) | 1.000 (Ref.) | ||
AC | 85 (36.3) | 93 (39.7) | 1.342 | 0.841~2.141 | 0.217 | |||
CC | 58 (24.8) | 65 (27.8) | 1.024 | 0.646~1.623 | 0.919 | |||
6 | HLA-DRB1 | rs3997872 | AA | 79 (33.8) | 77 (32.9) | 1.000 (Ref.) | ||
AT | 48 (20.5) | 61 (26.1) | 0.921 | 0.606~1.398 | 0.697 | |||
TT | 107 (45.7) | 96 (41.0) | 0.706 | 0.442~1.127 | 0.145 | |||
7 | CCR4 | rs2228428 | TT | 57 (24.4) | 52 (22.2) | 1.000 (Ref.) | ||
GT | 92 (39.3) | 103 (44.0) | 0.982 | 0.604~1.594 | 0.94 | |||
GG | 85 (36.3) | 79 (33.8) | 0.815 | 0.510~1.303 | 0.393 | |||
8 | C2 | rs9267673 | CC | 113 (48.3) | 113 (48.3) | 1.000 (Ref.) | ||
CT | 48 (20.5) | 53 (22.6) | 0.932 | 0.612~1.419 | 0.741 | |||
TT | 73 (31.2) | 68 (29.1) | 0.844 | 0.506~1.407 | 0.515 | |||
9 | TP53 | rs28934571 | CC | 81 (34.6) | 90 (38.5) | 1.000 (Ref.) | ||
AC | 92 (39.3) | 80 (34.1) | 0.944 | 0.595~1.498 | 0.808 | |||
AA | 61 (26.1) | 64 (27.4) | 1.207 | 0.761~1.914 | 0.425 | |||
10 | DEPDC5 | rs1012068 | TT | 62 (26.5) | 73 (31.2) | 1.000 (Ref.) | ||
GT | 85 (36.3) | 78 (33.3) | 1.234 | 0.785~1.941 | 0.362 | |||
GG | 87 (37.2) | 83 (35.5) | 1.283 | 0.812~2.027 | 0.285 | |||
11 | EGF | rs4444903 | AA | 92 (39.3) | 104 (44.4) | 1.000 (Ref.) | ||
AG | 86 (36.8) | 94 (40.2) | 1.034 | 0.690~1.551 | 0.871 | |||
GG | 56 (23.9) | 36 (15.4) | 1.758 | 1.062~2.911 | 0.028 | |||
12 | HULC | rs7763881 | AA | 78 (33.3) | 88 (37.6) | 1.000 (Ref.) | ||
AC | 70 (29.9) | 81 (34.6) | 0.67 | 0.430~1.044 | 0.077 | |||
CC | 86 (36.8) | 65 (27.8) | 0.653 | 0.415~1.028 | 0.066 | |||
13 | STAT4 | rs11889341 | GG | 94 (40.2) | 102 (43.6) | 1.000 (Ref.) | ||
GT | 72 (30.8) | 58 (24.8) | 1.003 | 0.651~1.545 | 0.99 | |||
TT | 68 (29.0) | 74 (31.6) | 1.351 | 0.838~2.178 | 0.217 | |||
14 | HLA-DQB1 | rs1049055 | AA | 77 (32.9) | 78 (33.3) | 1.000 (Ref.) | ||
AG | 54 (23.1) | 60 (25.6) | 0.92 | 0.605~1.400 | 0.698 | |||
GG | 103 (44.0) | 96 (41.1) | 0.839 | 0.529~1.330 | 0.455 | |||
15 | XRCC1 | rs25487 | GG | 120 (51.3) | 116 (49.6) | 1.000 (Ref.) | ||
GC | 49 (20.9) | 60 (25.6) | 1.083 | 0.700~1.676 | 0.719 | |||
CC | 65 (27.8) | 58 (24.8) | 0.789 | 0.501~1.245 | 0.309 | |||
16 | HSPA5 | rs430397 | CC | 57 (24.4) | 60 (25.6) | 1.000 (Ref.) | ||
CT | 107 (45.7) | 113 (48.3) | 0.828 | 0.502~1.364 | 0.458 | |||
TT | 70 (29.9) | 61 (26.1) | 0.825 | 0.535~1.273 | 0.385 | |||
17 | XRCC4 | rs1805377 | GG | 61 (26.1) | 69 (29.5) | 1.000 (Ref.) | ||
GA | 57 (24.3) | 65 (27.8) | 1.312 | 0.848~2.029 | 0.222 | |||
AA | 116 (49.6) | 100 (42.7) | 0.992 | 0.605~1.627 | 0.974 | |||
18 | SMARCA4 | rs11879293 | GG | 128 (54.7) | 115 (49.1) | 1.000 (Ref.) | ||
GA | 65 (27.8) | 64 (27.4) | 0.67 | 0.416~1.078 | 0.099 | |||
AA | 41 (17.5) | 55 (23.5) | 0.912 | 0.595~1.399 | 0.674 | |||
19 | MTHFR | rs9651118 | TT | 71 (30.3) | 65 (27.8) | 1.000 (Ref.) | ||
TG | 75 (32.1) | 71 (30.3) | 1.176 | 0.762~1.815 | 0.463 | |||
GG | 88 (37.6) | 98 (41.9) | 1.216 | 0.781~1.894 | 0.386 | |||
20 | ATF6 | rs2070150 | CC | 35 (15.0) | 50 (21.4) | 1.000 (Ref.) | ||
GC | 87 (37.1) | 70 (29.9) | 1.265 | 0.841~1.904 | 0.26 | |||
GG | 112 (47.9) | 114 (48.7) | 0.713 | 0.430~1.180 | 0.188 | |||
21 | SLIT3 | rs11134527 | AA | 97 (41.5) | 90 (38.5) | 1.000 (Ref.) | ||
AG | 81 (34.6) | 75 (32.1) | 1.002 | 0.655~1.533 | 0.992 | |||
GG | 56 (23.9) | 69 (29.4) | 0.753 | 0.478~1.186 | 0.221 | |||
22 | DICER1 | rs886037672 | TT | 122 (52.1) | 119 (50.9) | 1.000 (Ref.) | ||
TC | 94 (40.2) | 86 (36.8) | 1.066 | 0.319~1.148 | 0.124 | |||
CC | 18 (7.7) | 29 (12.3) | 0.605 | 0.319~1.148 | 0.124 | |||
23 | RAN | rs3803012 | AA | 104 (44.4) | 97 (41.5) | 1.000 (Ref.) | ||
AG | 61 (26.1) | 64 (27.3) | 0.889 | 0.569~1.390 | 0.606 | |||
GG | 69 (29.5) | 73 (31.2) | 0.882 | 0.574~1.355 | 0.566 | |||
24 | PIWIL1 | rs10773771 | TT | 106 (45.3) | 88 (37.6) | 1.000 (Ref.) | ||
TC | 47 (20.1) | 62 (26.5) | 0.801 | 0.528~1.214 | 0.295 | |||
CC | 81 (34.6) | 84 (35.9) | 0.629 | 0.629 | 0.055 | |||
25 | XRCC4 | rs2075685 | GG | 90 (38.5) | 86 (36.8) | 1.000 (Ref.) | ||
GT | 39 (16.6) | 51 (21.8) | 0.731 | 0.438~1.218 | 0.229 | |||
TT | 105 (44.9) | 97 (41.4) | 1.034 | 0.690~1.550 | 0.87 | |||
26 | SLFN12L | rs9909601 | GG | 120 (51.2) | 101 (43.2) | 1.000 (Ref.) | ||
GA | 28 (12.0) | 45 (19.2) | 0.958 | 0.644~1.425 | 0.834 | |||
AA | 86 (36.8) | 88 (37.6) | 0.648 | 0.374~1.120 | 0.12 | |||
27 | SLFN12L | rs1838149 | GG | 97 (41.5) | 86 (36.8) | 1.000 (Ref.) | ||
GA | 59 (25.2) | 70 (29.9) | 0.887 | 0.578~1.360 | 0.581 | |||
AA | 78 (33.3) | 78 (33.3) | 0.747 | 0.476~1.174 | 0.206 |