序号

基因

SNP

基因型

病例[n(%)]

对照[n(%)]

OR

95% CI

P

1

miR-34b/c

rs4938723

TT

70 (29.9)

81 (34.6)

1.000 (Ref.)

TC

105 (44.9)

113 (48.3)

1.075

0.709~1.630

0.732

CC

59 (25.2)

40 (17.1)

1.707

1.022~2.852

0.041

2

KIF1B

rs17401966

AA

111 (47.4)

101 (43.2)

1.000 (Ref.)

AG

95 (40.6)

86 (36.8)

1.005

0.676~1.495

0.98

GG

28 (12.0)

47 (20.0)

0.542

0.316~0.930

0.026

3

EFCAB11

rs12100561

AA

86 (36.7)

77 (32.9)

1.000 (Ref.)

AG

57 (24.4)

46 (19.7)

1.109

0.676~1.821

0.681

GG

91 (38.9)

111 (47.4)

0.734

0.485~1.110

0.143

4

BACH2

rs10944479

AA

64 (27.4)

68 (29.1)

1.000 (Ref.)

AC

86 (36.7)

91 (38.9)

0.84

0.529~1.334

0.461

CC

84 (35.9)

75 (32.0)

0.844

0.550~1.296

0.438

5

HLA-DRB1

rs2647073

AA

91 (38.9)

76 (32.5)

1.000 (Ref.)

AC

85 (36.3)

93 (39.7)

1.342

0.841~2.141

0.217

CC

58 (24.8)

65 (27.8)

1.024

0.646~1.623

0.919

6

HLA-DRB1

rs3997872

AA

79 (33.8)

77 (32.9)

1.000 (Ref.)

AT

48 (20.5)

61 (26.1)

0.921

0.606~1.398

0.697

TT

107 (45.7)

96 (41.0)

0.706

0.442~1.127

0.145

7

CCR4

rs2228428

TT

57 (24.4)

52 (22.2)

1.000 (Ref.)

GT

92 (39.3)

103 (44.0)

0.982

0.604~1.594

0.94

GG

85 (36.3)

79 (33.8)

0.815

0.510~1.303

0.393

8

C2

rs9267673

CC

113 (48.3)

113 (48.3)

1.000 (Ref.)

CT

48 (20.5)

53 (22.6)

0.932

0.612~1.419

0.741

TT

73 (31.2)

68 (29.1)

0.844

0.506~1.407

0.515

9

TP53

rs28934571

CC

81 (34.6)

90 (38.5)

1.000 (Ref.)

AC

92 (39.3)

80 (34.1)

0.944

0.595~1.498

0.808

AA

61 (26.1)

64 (27.4)

1.207

0.761~1.914

0.425

10

DEPDC5

rs1012068

TT

62 (26.5)

73 (31.2)

1.000 (Ref.)

GT

85 (36.3)

78 (33.3)

1.234

0.785~1.941

0.362

GG

87 (37.2)

83 (35.5)

1.283

0.812~2.027

0.285

11

EGF

rs4444903

AA

92 (39.3)

104 (44.4)

1.000 (Ref.)

AG

86 (36.8)

94 (40.2)

1.034

0.690~1.551

0.871

GG

56 (23.9)

36 (15.4)

1.758

1.062~2.911

0.028

12

HULC

rs7763881

AA

78 (33.3)

88 (37.6)

1.000 (Ref.)

AC

70 (29.9)

81 (34.6)

0.67

0.430~1.044

0.077

CC

86 (36.8)

65 (27.8)

0.653

0.415~1.028

0.066

13

STAT4

rs11889341

GG

94 (40.2)

102 (43.6)

1.000 (Ref.)

GT

72 (30.8)

58 (24.8)

1.003

0.651~1.545

0.99

TT

68 (29.0)

74 (31.6)

1.351

0.838~2.178

0.217

14

HLA-DQB1

rs1049055

AA

77 (32.9)

78 (33.3)

1.000 (Ref.)

AG

54 (23.1)

60 (25.6)

0.92

0.605~1.400

0.698

GG

103 (44.0)

96 (41.1)

0.839

0.529~1.330

0.455

15

XRCC1

rs25487

GG

120 (51.3)

116 (49.6)

1.000 (Ref.)

GC

49 (20.9)

60 (25.6)

1.083

0.700~1.676

0.719

CC

65 (27.8)

58 (24.8)

0.789

0.501~1.245

0.309

16

HSPA5

rs430397

CC

57 (24.4)

60 (25.6)

1.000 (Ref.)

CT

107 (45.7)

113 (48.3)

0.828

0.502~1.364

0.458

TT

70 (29.9)

61 (26.1)

0.825

0.535~1.273

0.385

17

XRCC4

rs1805377

GG

61 (26.1)

69 (29.5)

1.000 (Ref.)

GA

57 (24.3)

65 (27.8)

1.312

0.848~2.029

0.222

AA

116 (49.6)

100 (42.7)

0.992

0.605~1.627

0.974

18

SMARCA4

rs11879293

GG

128 (54.7)

115 (49.1)

1.000 (Ref.)

GA

65 (27.8)

64 (27.4)

0.67

0.416~1.078

0.099

AA

41 (17.5)

55 (23.5)

0.912

0.595~1.399

0.674

19

MTHFR

rs9651118

TT

71 (30.3)

65 (27.8)

1.000 (Ref.)

TG

75 (32.1)

71 (30.3)

1.176

0.762~1.815

0.463

GG

88 (37.6)

98 (41.9)

1.216

0.781~1.894

0.386

20

ATF6

rs2070150

CC

35 (15.0)

50 (21.4)

1.000 (Ref.)

GC

87 (37.1)

70 (29.9)

1.265

0.841~1.904

0.26

GG

112 (47.9)

114 (48.7)

0.713

0.430~1.180

0.188

21

SLIT3

rs11134527

AA

97 (41.5)

90 (38.5)

1.000 (Ref.)

AG

81 (34.6)

75 (32.1)

1.002

0.655~1.533

0.992

GG

56 (23.9)

69 (29.4)

0.753

0.478~1.186

0.221

22

DICER1

rs886037672

TT

122 (52.1)

119 (50.9)

1.000 (Ref.)

TC

94 (40.2)

86 (36.8)

1.066

0.319~1.148

0.124

CC

18 (7.7)

29 (12.3)

0.605

0.319~1.148

0.124

23

RAN

rs3803012

AA

104 (44.4)

97 (41.5)

1.000 (Ref.)

AG

61 (26.1)

64 (27.3)

0.889

0.569~1.390

0.606

GG

69 (29.5)

73 (31.2)

0.882

0.574~1.355

0.566

24

PIWIL1

rs10773771

TT

106 (45.3)

88 (37.6)

1.000 (Ref.)

TC

47 (20.1)

62 (26.5)

0.801

0.528~1.214

0.295

CC

81 (34.6)

84 (35.9)

0.629

0.629

0.055

25

XRCC4

rs2075685

GG

90 (38.5)

86 (36.8)

1.000 (Ref.)

GT

39 (16.6)

51 (21.8)

0.731

0.438~1.218

0.229

TT

105 (44.9)

97 (41.4)

1.034

0.690~1.550

0.87

26

SLFN12L

rs9909601

GG

120 (51.2)

101 (43.2)

1.000 (Ref.)

GA

28 (12.0)

45 (19.2)

0.958

0.644~1.425

0.834

AA

86 (36.8)

88 (37.6)

0.648

0.374~1.120

0.12

27

SLFN12L

rs1838149

GG

97 (41.5)

86 (36.8)

1.000 (Ref.)

GA

59 (25.2)

70 (29.9)

0.887

0.578~1.360

0.581

AA

78 (33.3)

78 (33.3)

0.747

0.476~1.174

0.206