SNP | 基因型 | 病例[n(%)] | 对照[n(%)] | OR* | 95% CI* | P值* |
rs4938723 | 共显性模型 | |||||
TT | 70 (29.9) | 81 (34.6) | 1.000 (Ref.) | |||
TC | 105 (49.9) | 11 (48.3) | 1.081 | 0.711~1.642 | 0.716 | |
CC | 59 (25.2) | 40 (17.1) | 1.736 | 1.036~2.910 | 0.036 | |
显性模型 | ||||||
TT | 70 (29.9) | 81 (34.6) | 1.000 (Ref.) | |||
TC + CC | 164 (70.1) | 15 (65.4) | 1.251 | 0.846~1.849 | 0.261 | |
隐性模型 | ||||||
TT + TC | 175 (74.8) | 19 (82.9) | 1.000 (Ref.) | |||
CC | 59 (25.2) | 40 (17.1) | 1.658 | 1.054~2.609 | 0.029 | |
rs4444903 | 共显性模型 | |||||
AA | 92 (39.3) | 10 (44.4) | 1.000 (Ref.) | |||
AG | 86 (36.8) | 94 (40.2) | 1.058 | 0.701~1.596 | 0.788 | |
GG | 56 (23.9) | 36 (15.4) | 1.841 | 1.103~3.071 | 0.019 | |
显性模型 | ||||||
AA | 92 (39.3) | 104 (44.4) | 1.000 (Ref.) | |||
AG + GG | 142 (60.7) | 13 (55.6) | 1.272 | 0.876~1.849 | 0.207 | |
隐性模型 | ||||||
AA + AG | 178 (76.1) | 19 (84.6) | 1.000 (Ref.) | |||
GG | 56 (23.9) | 36 (15.4) | 1.791 | 1.118~2.870 | 0.015 | |
rs17401966 | 共显性模型 | |||||
AA | 111 (47.4) | 10 (43.2) | 1.000 (Ref.) | |||
AG | 95 (40.6) | 86 (36.7) | 1.014 | 0.678~1.516 | 0.946 | |
GG | 28 (12.0) | 47 (20.1) | 0.540 | 0.314~0.930 | 0.026 | |
显性模型 | ||||||
AA | 111 (47.4) | 101 (43.2) | 1.000 (Ref.) | |||
AG + GG | 123 (52.6) | 13 (56.8) | 0.844 | 0.584~1.220 | 0.367 | |
rs17401966 | 隐性模型 | |||||
AA + AG | 206 (88.0) | 18 (79.9) | 1.000 (Ref.) | |||
GG | 28 (12.0) | 47 (20.1) | 0.537 | 0.322~0.895 | 0.017 |