疾病

菌群变化描述

肠道疾病

溃疡性结肠炎 [41]

Clostridium symbiosum增多;

Verrucomicrobia, Leuconostocaceae, Ruminococcaceae, Lachnospiraceae减少;

克罗恩病 [42]

G. moniliformis, A. brassicicola, C. neoformans, Candida spp.增多;

Synergistetes, Verrucomicrobia减少;

肠易激综合症 [43]

Enterococcaceae, Yersiniaceae, Streptococcus sp.增多;

结直肠癌 [44]

Aspergillus rambellii, Cordyceps sp. RAO-2017, Erysiphe pulchra, Moniliophthora perniciosa, Sphaerulina musiva, Phytophthora capsici增多;

Aspergillus kawachii减少;

乳糜泻 [45]

L. bacterium, D. invisus, Parabacteroides sp.增多;

B. vulgatus_str_3775_S_1080 branch, B.unformis_ATCC_8492减少;

肠外疾病

肥胖 [39] [46] [47] [48]

Firmicutes增多;

Akkermansia muciniphila, Faecalibacterium prausnitzii, Bacteroides, Osillibacter, Alistipes减少;

二型糖尿病 [49]

Dallella增多;

Bifidobacteria, Akkermansia减少;

非酒精性脂肪肝 [50]

Ruminococcus, F. prausnitzii, Coprococcus减少;

心血管疾病 [51]

Prevotella, Tyzzerella增多;

Alloprevotella, Catenibacterium减少;

高血压 [52]

Prevotella增多;

Faecalibacterium, Oscillibacter, Roseburia, Bifidobacterium, Coprococcus Butyrivibrio减少;

动脉粥样硬化 [53]

Enterobacteriaceae and Streptococcus spp.增多;

帕金森 [54]

Akkermansia, Catabacter, Lactobacillaceae, Akkermansiaceae增多; Roseburia, Faecalibacterium, LachnospiraceaeND3007, Lachnospiraceae减少;

阿尔茨海默症 [55]

Ruminococcaceae, Enterococcaceae, Lactobacillaceae增多; Lanchnospiraceae, Bacteroidaceae, Veillonellaceae减少

自闭症谱系障碍 [56]

Lactobacillus, Bacteroides, Desulfovibrio, and Clostridium增多;

Bifidobacterium, Blautia, Dialister, Prevotella, Veillonella, Turicibacter减少;

肌萎缩侧索硬化 [57]

Lachnospira增多;

Oscillibacter, Anaerostipes, Lachnospiraceae减少;

焦虑抑郁 [58]

Coprococcus and Dialister减少;

肿瘤 [59]

Pseudoxanthomona, Saccharopolsypora, Streptomyces增多

皮肤病 [60]

Akkermansia, Ruminoccocus减少