Compd | R | pIC50 (HCT116) | pIC50(A2780) | ||
Exper | Pred | Exper | Pred | ||
1 |
| 4.94 | 5.16 | 4.26 | 4.40 |
2 |
| 5.29 | 5.16 | 4.40 | 4.40 |
3* |
| 5.69 | 5.46 | 4.48 | 4.40 |
4 |
| 5.51 | 5.45 | 4.67 | 4.70 |
5 |
| 5.64 | 5.52 | 4.77 | 4.76 |
6* |
| 5.96 | 5.58 | 4.83 | 4.80 |
7 |
| 5.18 | 5.16 | 4.56 | 4.40 |
8 |
| 5.60 | 5.76 | 4.89 | 5.06 |
9* |
| 5.85 | 5.59 | 4.68 | 4.89 |
10 |
| 5.88 | 6.01 | 5.00 | 5.04 |
11 |
| 6.60 | 6.51 | 5.69 | 5.39 |