| 激酶 | 靶标配体 | E3连接酶 |
| BCR-ABL | imatinib, bosutinib, dasatinib, ponatinib | CRBN, VHL |
| BTK | Ibrutinib, CGI1746, zanubrutinib | CRBN, VHL, IAP |
| FAK | Defactinib, PND-1186, PF562271 | CRBN, VHL |
| Wee1 | AZD1775 | CRBN, VHL |
| TRK | Entrectinib, GNF-8625 | CRBN, VHL |
| IRAK4 | / | CRBN, VHL, IAP, MDM2 |
| LRKK2 | DNL151, DNL201 | CRBN, VHL |
| B-Raf | PLX8394, Vemurafenib | CRBN, VHL |
| CDK | Palbociclib, ribociclib, abemaciclib, SNS-032, Torin1, CCT251545, Cortistatin-17 | CRBN, VHL, IAP, MDM2 |
| TBK1 | MRT67307 | VHL |
| EGFR | Vandetanib, Canertinib, osimertinib | VHL, CRBN |
| FLT3 | AC220 | CRBN |