临床资料 | COPD组 (n = 150) | COPD合并肺癌组 (n = 79) | 检验统计量 | P值 |
吸烟指数(年支) | 600.000 (0.0, 900.0) | 800.000 (400.0, 1200.0) | 4423.0 | 0.002 |
EOS (*109/L) | 0.16 (0.1, 0.3) | 0.11 (0.1, 0.2) | 4916.5 | 0.034 |
Hb (g/L) | 145 (136, 153) | 134 (117, 146) | 3676.0 | 0.000 |
PLT (*109/L) | 218 (184.5, 258) | 233 (184, 306) | 5252.5 | 0.182 |
CRP (mg/L) | 1.09 (0.5, 3.6) | 9.445 (2.6, 27.7) | 2121.5 | 0.000 |
纤维蛋白原(g/L) | 3.1 (2.5, 3.7) | 4.14 (3.2, 5.2) | 2116.5 | 0.000 |
FDP (ug/mL) | 1.9 (1.1, 2.5) | 2.5 (2.0, 3.8) | 2100 | 0.000 |
D-Di (ug/mL) | 0.310.2, 0.4) | 0.51 (0.3, 1.0) | 3085 | 0.000 |
脂蛋白(a) (ng/dL) | 15.6 (8.1, 29.9) | 21.155 (15.0, 47.8) | 3249.5 | 0.000 |
载脂蛋白A1/B | 1.24 (1.0, 1.6) | 1.205 (1.0, 1.4) | 4105 | 0.094 |
低密度脂蛋白(mmol/L) | 2.8 (2.3, 3.2) | 2.63 (2.3, 3.1) | 4311.5 | 0.268 |
NLR | 1.864 (1.5, 2.6) | 3.078 (2.2, 4.9) | 3055 | 0.000 |
唾液酸(ng/L) | 575.0 (517.5, 666.5) | 709.5 (595.5, 823.3) | 2630.5 | 0.000 |
MHR | 0.443 (0.3, 0.6) | 0.52 (0.4, 0.7) | 3793.5 | 0.015 |
AFP (IU/mL) | 2.5 (1.7, 3.7) | 2.36 (1.8, 3.4) | 3188.5 | 0.673 |
癌胚抗原(ng/mL) | 2.56 (1.8, 3.9) | 4.325 (2.6, 8.4) | 3521 | 0.000 |
血清总胆汁酸(umol/L) | 2.98 (1.8, 5.0) | 3 (2.2, 5) | 5296 | 0.306 |
β2-微球蛋白(mg/L) | 1.605 (1.4, 1.9) | 10.9 (9.5, 13.2) | 60 | 0.000 |
阴离子间隙(mmol/L) | 11.7 (10.1, 13.4) | 1.94 (1.6, 2.9) | 707.5 | 0.000 |
乳酸脱氢酶(U/L) | 180.82 (153.2, 215.7) | 208.7 (179.2, 255.8) | 1539 | 0.002 |
肌酸激酶(U/L) | 97.7 (71.8, 140.1) | 71.7 (47, 114.5) | 1640.5 | 0.005 |
α-羟丁酸脱氢酶(U/L) | 126.85 (104.7, 141.3) | 133.78 (113.4, 171.2) | 1640.5 | 0.013 |
甘油三酯(mmol/L) | 1.08 (0.8, 1.4) | 0.96 (0.8, 1.4) | 4384.5 | 0.316 |
尿素氮(mmol/L) | 5.52 (4.4, 6.5) | 5.295 (4.1, 6.6) | 5133 | 0.197 |
γ-谷氨酰转移酶(U/L) | 24.62 (18.2, 42.5) | 26.635 (19.2, 46.9) | 5422 | 0.365 |
ALT/AST | 0.94 (0.8, 1.2) | 0.79 (0.6, 1.1) | 4241 | 0.001 |
AST (U/L) | 19.78 (16.5, 23.5) | 19.33 (15.6, 23.5) | 5529.5 | 0.453 |
ALT (U/L) | 18.965 (14.5, 26.3) | 13.84 (9.8, 20.9) | 4012.5 | 0.000 |
CA-125 (U/mL) | 8.605 (6.3, 12.4) | 19.89 (11.0, 54.3) | 1218 | 0.000 |
白球比 | 1.465 (1.4, 1.6) | 1.26 (1.1, 1.5) | 3128 | 0.000 |
PCT (ng/mL) | 0.1 (0.0, 0.1) | 0.1 (0.0, 0.1) | 1997.5 | 0.438 |
CA-199 (U/mL) | 7.09 (4.9, 14.3) | 10.625 (4.8, 24.3) | 2182 | 0.125 |
NSE (ng/mL) | 12.71 (11.2, 15.1) | 16.1 (12.4, 22.3) | 2860.5 | 0.000 |
ESR (mm/h) | 9 (6.0, 18.8) | 23 (13.8, 44.8) | 1640.5 | 0.000 |
可溶性细胞角蛋白19片段(ng/mL) | 2.515 (1.8, 3.2) | 4.24 (3.0, 7.6) | 2547 | 0.000 |
年龄(岁) | 60.35 ± 8.34 | 64.41 ± 4.31 | 16.375 | 0.000 |
BMI (Kg/m2) | 24.41 ± 3.55 | 23.17 ± 3.58 | 6.293 | 0.013 |
WBC (*109/L) | 6.76 ± 1.58 | 7.63 ± 2.07 | 12.607 | 0.000 |
淋巴细胞计数(*109/L) | 2.15 ± 2.20 | 2.89 ± 9.03 | 0.907 | 0.342 |
单核细胞计数(*109/L) | 0.52 ± 0.17 | 0.71 ± 0.98 | 5.059 | 0.025 |
中性粒细胞计数(*109/L) | 4.01 ± 1.47 | 5.18 ± 1.76 | 28.896 | 0.000 |
嗜碱性粒细胞计数(*109/L) | 0.07 ± 0.39 | 0.04 ± 0.13 | 0.301 | 0.584 |
红细胞计数(*1012/L) | 4.64 ± 0.49 | 4.35 ± 0.64 | 15.173 | 0.000 |
血小板压积(%) | 0.66 ± 3.49 | 0.34 ± 0.85 | 0.677 | 0.411 |
凝血酶原时间(S) | 12.42 ± 0.93 | 12.98 ± 1.23 | 14.757 | 0.000 |
碱性磷酸酶(U/L) | 80.73 ± 22.86 | 99.84 ± 45.58 | 17.809 | 0.000 |
甘胆酸(mg/L) | 1.67 ± 1.22 | 1.92 ± 1.40 | 1.399 | 0.239 |
高密度脂蛋白(mmol/L) | 1.17 ± 0.31 | 1.10 ± 0.28 | 2.886 | 0.091 |
ALI | 570.43 ± 484.28 | 481.15 ± 1121.39 | 0.704 | 0.402 |
AAPR | 0.57 ± 0.41 | 0.42 ± 0.15 | 9.918 | 0.002 |
载脂蛋白B (g/L) | 1.02 ± 0.26 | 0.98 ± 0.23 | 1.259 | 0.263 |
PLR | 127.55 ± 87.39 | 166.61 ± 89.04 | 10.202 | 0.002 |
游离脂肪酸(mmol/L) | 0.38 ± 0.16 | 0.41 ± 0.21 | 1.510 | 0.220 |
血磷(mmol/L) | 1.13 ± 0.17 | 1.14 ± 0.20 | 0.009 | 0.923 |
血镁(mmol/L) | 0.89 ± 0.09 | 0.88 ± 0.08 | 0.980 | 0.323 |
血钙(mmol/L) | 2.54 ± 2.58 | 2.29 ± 0.21 | 0.736 | 0.392 |
载脂蛋白A1 (g/L) | 1.30 ± 0.29 | 1.16 ± 0.33 | 9.834 | 0.002 |
总胆固醇(mmol/L) | 4.74 ± 1.03 | 4.48 ± 0.90 | 2.928 | 0.088 |
胱抑素(mg/L) | 1.55 ± 6.68 | 0.97 ± 0.25 | 0.417 | 0.520 |
补体C1q (mg/L) | 263.90 ± 1135.29 | 192.13 ± 44.05 | 0.311 | 0.578 |
尿酸(umol/L) | 363.48 ± 96.32 | 374.56 ± 329.43 | 0.144 | 0.704 |
肌酐(umol/L) | 72.05 ± 10.54 | 70.07 ± 15.02 | 1.327 | 0.251 |
腺苷脱氨酶(U/L) | 9.23 ± 3.66 | 10.91 ± 5.29 | 7.932 | 0.005 |
直接胆红(umol/L) | 2.49 ± 0.93 | 2.54 ± 0.93 | 0.139 | 0.709 |
APTTA比值 | 1.09 ± 0.31 | 1.13 ± 0.15 | 0.845 | 0.359 |
间接胆红(umol/L) | 10.72 ± 3.81 | 9.56 ± 3.48 | 5.046 | 0.026 |
PT活动度(%) | 103.12 ± 14.96 | 96.79 ± 13.72 | 9.773 | 0.002 |
白蛋白(g/L) | 39.90 ± 3.42 | 36.71 ± 4.69 | 34.517 | 0.000 |
球蛋白(g/L) | 27.54 ± 5.37 | 29.44 ± 4.87 | 6.890 | 0.009 |
总胆红(umol/L) | 13.24 ± 4.64 | 12.01 ± 4.24 | 3.842 | 0.051 |
总蛋白(g/L) | 67.11 ± 7.48 | 66.15 ± 6.22 | 0.947 | 0.331 |
鳞癌抗原(ng/mL) | 1.81 ± 4.12 | 2.35 ± 4.35 | 0.754 | 0.386 |
PT国际标准化比值 | 1.64 ± 8.25 | 2.08 ± 9.34 | 0.132 | 0.716 |
活化部分凝血酶原时间(S) | 34.14 ± 5.34 | 35.91 ± 6.02 | 5.162 | 0.024 |