| Characteristic | Groups | Control group | Observation group | P-value | |
| Age (years) | (44.76 ± 11.52) | (50.34 ± 8.91) | <0.001 | ||
| BMI (kg/m2) | (24.92 ± 3.69) | (25.61 ± 3.40) | 0.080 | ||
| Tumor Size (cm) | (1.20 ± 0.74) | (0.83 ± 0.61) | <0.001 | ||
| Multifocality, n (%) | No | 212 (64.8) | 68 (67.3) | 0.645 | |
| Yes | 115 (35.2) | 33 (32.7) | |||
| Hashimoto thyroiditis, n (%) | No | 246 (75.2) | 85 (84.2) | 0.061 | |
| Yes | 81 (24.8) | 16 (15.8) | |||
| Extrathyroidal Extension, n (%) | No | 163 (49.8) | 67 (66.3) | 0.004 | |
| Yes | 164 (50.2) | 34 (33.7) | |||
| Lymph Node Metastasis, n (%) | No | 175 (53.5) | 75 (74.3) | <0.001 | |
| Yes | 152 (46.5) | 26 (25.7) | |||
| Distant Metastasis, n (%) | No | 323 (98.8) | 100 (99) | 0.849 | |
| Yes | 4 (1.2) | 1 (1) | |||