lncRNA

Expression

Mechanism

Biological function

BCAR4

Up

ERBB2/3 signaling

Promotes breast cancer tamoxifen resistance [13]

Hedgehog/GLI2 signaling

Promotes breast cancer metastasis [14]

Hippo and Hedgehog signaling

Promotes YAP-dependent glycolysis [15]

LUCAT1

Up

miR-5582-3p, TCF7L2 and Wnt/β-catenin signaling

Increases stem-like properties of breast cancer cells [16]

miR-5702

Increases cell proliferation, metastasis and cell cycle progression, and suppresses cell apoptosis [17]

SPRY4-

IT1

Up

ZNF703

Promotes cell proliferation and inhibites cell apoptosis [18]

miR-6882-3p, TCF7L2

Promotes cell proliferation and stemness [19]

LINC

00511

Up

miR-185-3p, E2F1

Promotes cell proliferation, sphere-formation ability, stem factors expression and tumor growth [20]

miR-150, MMP13

Promotes cell proliferation, migration and invasion [21]

miR-185, STXBP4

LINC00511 knockdown restricted cell proliferation, promoted cell apoptosis, and enhanced radiosensitivity [22]

miR-29c, CDK6

LINC00511 knockdown enhanced paclitaxel cytotoxicity [23]

TINCR

Up

miR-7, KLF4

Stimulates cell proliferation, anchorage-independent growth and suppresses cell apoptosis [24]

miR‑589‑3p,

IGF1R‑AKT pathway

Promotes cell proliferation, migration and invasion, and inhibites cell apoptosis. [25]

miR-503-5p, EGFR, JAK2-STAT3 signaling

Promotes cell proliferation,invasion, colony formation,and tumor growth [26]

miR-125b

Promotes trastuzumab resistance [27]