Entry | R1 | R2 | Substrate | Product | Time (h) | Yield (%)b | ee (%)c |
1 | 4-CH3C6H4 | Ph | 2b | 3b | 48 96 144 | 15 34 46 | 73 68 67 |
2 | 3-CH3C6H4 | Ph | 2c | 3c | 48 96 144 | 22 35 51 | 79 76 74 |
3 | 4-ClC6H4 | Ph | 2d | 3d | 48 96 120 | 29 42 53 | 74 71 68 |
4 | 4-FC6H4 | Ph | 2e | 3e | 48 96 120 | 28 48 52 | 76 73 72 |
5 | 2-ClC6H4 | Ph | 2f | 3f | 48 72 96 | 5 8 11 | 58 58 58 |
6 | Ph | 4-ClC6H4 | 2g | 3g | 48 96 144 | 34 59 70 | 70 70 70 |
7 | Ph | 4-CH3C6H4 | 2h | 3h | 48 96 144 | 32 48 57 | 32 39 42 |