|
| Overall | IL-6 levels | P-value | ||
| Tertile 1 | Tertile 2 | Tertile 3 | |||
| 人口特征 |
| 0 < IL-6 < 4.69 (n = 39) | 4.69 ≤ IL-6 < 11.29 (n = 40) | 11.29 ≤ IL-6 (n = 41) |
|
| 年龄(岁) | 68.50 (62.25, 75.75) | 70.00 (63.00, 79.00) | 66.50 (59.50, 74.50) | 67.00 (57.50, 76.50) | 0.412 |
| 女n (%) | 56 (46.7%) | 21 (53.8%) | 13 (32.5%) | 22 (53.7%) | 0.089 |
| BMI (kg/m2) | 24.74 (22.49, 27.26) | 24.77 (22.43, 27.68) | 24.63 (22.40, 28.68) | 24.69 (22.63, 26.20) | 0.724 |
| 心率(次/min) | 79.00 (67.00, 89.75) | 72.00 (61.00, 88.00) | 79.00 (68.50, 88.00) | 81.00 (71.00, 90.00) | 0.185 |
| 收缩压(mmHg) | 128.00 (114.25, 142.75) | 124.00 (108.00, 137.00) | 130.50 (115.50, 146.00) | 130.00 (119.50, 137.50) | 0.147 |
| 舒张压(mmHg) | 75.16 ± 13.50 | 72.64 ± 14.30 | 77.68 ± 11.59 | 75.20 ± 14.31 | 0.335 |
| 吸烟史 | 25 (20.8%) | 6 (15.4%) | 12 (30.0%) | 7 (17.1%) | 0.213 |
| 饮酒史 | 23 (19.2%) | 7 (17.9%) | 11 (27.5%) | 5 (12.2%) | 0.211 |
| 既往史 | |||||
| 高血压 | 80 (66.7%) | 29 (74.4%) | 25 (62.5%) | 26 (63.4%) | 0.462 |
| 糖尿病 | 35 (29.2%) | 12 (30.8%) | 10 (25.0%) | 13 (31.7%) | 0.774 |
| 血运重建 | 70 (58.3%) | 21 (53.8%) | 23 (57.5%) | 26 (63.4%) | 0.68 |
| 房颤 | 38 (31.7%) | 20 (51.3%) | 9 (22.5%) | 9 (22.0%) | 0.006 |
| 高脂血症 | 34 (28.3%) | 9 (23.1%) | 11 (27.5%) | 14 (34.1%) | 0.542 |
| 心功能相关指标 | |||||
| NYHA 心功能分级* | 52 (43.3%) | 14 (35.9%) | 22 (55.0%) | 16 (39.0%) | 0.182 |
| 心衰用药 | |||||
| ACEI/ARB | 10 (8.3%) | 2 (5.1%) | 3 (7.5%) | 5 (12.2%) | 0.506 |
| ARNi | 39 (32.5%) | 15 (38.5%) | 15 (37.5%) | 9 (22.0%) | 0.205 |
| Beta Blocker | 59 (49.2%) | 23 (59.0%) | 21 (52.5%) | 15 (36.6%) | 0.118 |
| SGLT2i | 28 (23.3%) | 12 (30.8%) | 8 (20.0%) | 8 (19.5%) | 0.409 |
| 螺内酯 | 57 (47.5%) | 23 (59.0%) | 18 (45.0%) | 16 (39.0%) | 0.188 |
| 超声心动图指标 | |||||
| LVEF (%) | 55.00 (45.00, 61.00) | 55.00 (42.00, 61.00) | 53.50 (45.25, 59.75) | 55.00 (45.00, 61.00) | 0.712 |
| TAPSE (cm) | 2.00 (1.90, 2.12) | 2.00 (2.00, 2.10) | 2.00 (1.80, 2.12) | 2.00 (1.80, 2.20) | 0.794 |
| PASP (mmHg) | 36.63 (27.25, 40.00) | 36.63 (28.00, 38.00) | 34.00 (26.00, 39.75) | 38.00 (28.50, 44.50) | 0.328 |
| E’ (cm/s) | 8.00 (5.50, 14.96) | 8.00 (5.90, 14.96) | 7.88 (5.50, 14.96) | 8.00 (5.35, 14.96) | 0.573 |
| E/A | 96 (80.0%) | 33 (84.6%) | 32 (80.0%) | 31 (75.6%) | 0.603 |
| 实验室检测指标 | |||||
| 胆固醇(mmol/L) | 4.14 (3.31, 4.90) | 4.18 (3.27, 4.71) | 4.13 (3.31, 4.90) | 4.01 (3.33, 4.97) | 0.889 |
| 甘油三酯(mmol/L) | 1.06 (0.76, 1.35) | 1.07 (0.80, 1.28) | 0.91 (0.69, 1.28) | 1.25 (0.77, 1.77) | 0.178 |
| 低密度脂蛋白(mmol/L) | 2.35 (1.76, 2.99) | 2.38 (1.66, 3.03) | 2.32 (1.87, 3.08) | 2.36 (1.74, 2.94) | 0.976 |
| 高密度脂蛋白(mmol/L) | 1.09 (0.92, 1.31) | 1.15 (0.92, 1.35) | 1.08 (0.96, 1.23) | 1.06 (0.85, 1.29) | 0.631 |
| C-反应蛋白(mg/L) | 26.35 (12.15, 30.52) | 25.23 (13.00, 29.88) | 18.41 (8.71, 30.52) | 28.00 (12.70, 42.26) | 0.158 |
| NT-proBNP (pg/ml) | 1458.90 (719.60, 2330.00) | 1271.00 (818.00, 2209.00) | 1541.90 (577.75, 2186.50) | 1555.00 (648.60, 3773.50) | 0.714 |
| 肌红蛋白(μg/mL) | 70.65 (42.20, 91.22) | 54.00 (30.00, 91.22) | 74.09 (46.50, 91.22) | 84.17 (40.50, 91.22) | 0.236 |
| 肌酸激酶同工酶(μg/mL) | 3.55 (1.24, 12.39) | 2.52 (0.70, 12.39) | 12.39 (1.50, 12.39) | 2.40 (1.21, 12.39) | 0.155 |
| 高敏肌钙蛋白-I (μg/mL) | 0.35 (0.04, 9.83) | 0.35 (0.02, 2.55) | 0.35 (0.10, 9.83) | 0.35 (0.03, 9.83) | 0.228 |
| 糖化血红蛋白A1c (mmol/L) | 6.49 (6.00, 6.63) | 6.49 (6.10, 6.63) | 6.49 (5.90, 6.63) | 6.50 (6.05, 6.91) | 0.287 |
| 脂蛋白a (mg/L) | 196.50 (91.00, 294.75) | 191.00 (91.00, 340.00) | 199.50 (84.04, 273.75) | 188.00 (91.00, 281.00) | 0.763 |
| 载脂蛋白A1 (g/L) | 1.19 (0.99, 1.38) | 1.18 (1.02, 1.45) | 1.20 (1.01, 1.36) | 1.14 (0.88, 1.31) | 0.31 |
| 载脂蛋白B (g/L) | 0.77 (0.62, 0.91) | 0.77 (0.54, 0.86) | 0.79 (0.63, 0.91) | 0.77 (0.62, 1.02) | 0.695 |
| APOB/APOA | 0.68 (0.54, 0.81) | 0.60 (0.47, 0.83) | 0.68 (0.56, 0.78) | 0.68 (0.57, 0.84) | 0.571 |
| 血钙(mmol/L) | 2.21 (2.13, 2.31) | 2.30 (2.16, 2.36) | 2.21 (2.15, 2.26) | 2.19 (2.05, 2.25) | 0.026 |
| 血磷(mmol/L) | 1.04 (0.92, 1.17) | 1.04 (0.94, 1.17) | 1.09 (0.97, 1.23) | 1.03 (0.87, 1.15) | 0.375 |