Entry

2a: NaBH₄ (equiv.)

Solvent

Time/h

Yield/%

1

1.1:1

DCE

2.5

trace

2

1.1:1

MeOH

1.5

86

3

1.1:1

CAN

2.0

22

4

1.1:1

THF

1.5

49

5

1.1:1

EtOH

1.5

16

6

1.1:1

DMF

2.0

14

7

1.1:1

DMSO

2.5

Trace

8

1.1:1

EA

1.5

86

9

1.1:1

PhH

2.0

Trace

10

1.1:1

H₂O

1.5

86

11

0.9:1

H₂O

1.5

72

12

1.0:1

H₂O

1.5

83

13

1.2:1

H₂O

1.5

86

14

1.1:0.9

H₂O

1.5

77

15

1.1:1.2

H₂O

1.5

86