Group¹

A

B

C

D

E

F

1 weeks

AST (U/L)²

70.6 ± 2.3

240.1 ± 46.0

172.5 ± 22.4

167.7 ± 12.0

135.4 ± 10.4^*

202.9 ± 28.7

ALT (U/L)

39.6 ± 1.8

188.3 ± 34.0^###

136.8 ± 22.9

117.6 ± 8.5

97.8 ± 9.6^*

176.0 ± 26.2

3 weeks

AST (U/L)

61.8 ± 2.1

657.0 ± 103.3^###

374.9 ± 56.2

365.5 ± 38.4^**

345.1 ± 15.7^**

542.1 ± 57.4

ALT (U/L)

33.1 ± 1.3

558.5 ± 22.5^###

356.5 ± 37.7^**

336.1 ± 37.8^**

315.2 ± 23.3^***

569.9 ± 53.4

6 weeks

AST (U/L)

71.3 ± 2.0

1515.2 ± 228.5^###

918.1 ± 91.0^*

683.1 ± 80.6

700.9 ± 61.0^**

1704.9 ± 270.4

ALT (U/L)

47.4 ± 3.0

1553.8 ± 166.3^###

1091.6 ± 113.2

660.8 ± 60.1^**

627.6 ± 57.6^**

1722.2 ± 304.5

8 weeks

AST (U/L)

73.7 ± 2.1

1848.1 ± 156.4^###

1445.2 ± 165.3

1122.6 ± 134.8^*

1202.6 ± 125.6^*

1597.7 ± 334.3

ALT (U/L)

52.2 ± 3.0

1595.8 ± 178.5^###

1717.8 ± 205.4

1223.7 ± 125.5

942.2 ± 79.2^*

1188.2 ± 268.4

6 weeks

Albumin (g/dL)

3.37 ± 0.06

2.95 ± 0.07^###

3.13 ± 0.08

3.16 ± 0.08

3.27 ± 0.04^**

2.82 ± 0.07

8 weeks

Albumin (g/dL)

3.23 ± 0.04

2.24 ± 0.09^###

2.58 ± 0.10^*

2.60 ± 0.11^*

2.70 ± 0.10^**

2.20 ± 0.08