Item | 空白组 | 对照组 | 低剂量组 | 高剂量组 | ||||||||
Naïve | Vehicle | Low-dose 2.5 mg/kg b.w | High-dose 25 mg/kg b.w. | |||||||||
Glucose (mg/dL) | 396.2 | ± | 101.4 | 407.4 | ± | 90.1 | 392.4 | ± | 43.7 | 342.0 | ± | 74.9 |
BUN (mg/dL) | 19.1 | ± | 2.2 | 19.2 | ± | 3.3 | 18.8 | ± | 1.4 | 19.4 | ± | 2.6 |
Creatinine (mg/dL) | 1.18 | ± | 0.11 | 1.33 | ± | 0.19 | 1.18 | ± | 0.08 | 1.09 | ± | 0.11* |
AST (U/L) | 62.4 | ± | 98.2 | 23.4 | ± | 6.1 | 19.6 | ± | 4.3 | 19.4 | ± | 3.5 |
ALT (U/L) | 68.6 | ± | 36.3 | 57.2 | ± | 15.6 | 60.2 | ± | 13.6 | 48.6 | ± | 11.2 |
Total protein (g/dL) | 6.1 | ± | 0.2 | 6.2 | ± | 0.3 | 5.9 | ± | 0.3 | 5.9 | ± | 0.4 |
Albumin (g/dL) | 4.06 | ± | 0.17 | 4.02 | ± | 0.15 | 3.94 | ± | 0.23 | 4.04 | ± | 0.26 |
ALP (U/L) | 125.8 | ± | 12.1 | 116.6 | ± | 23.7 | 181.4 | ± | 82.8 | 147.6 | ± | 27.6 |
Cholesterol (mg/dL) | 71.0 | ± | 15.9 | 85.0 | ± | 23.4 | 65.0 | ± | 21.8 | 68.8 | ± | 19.8 |
Triglyceride (mg/dL) | 63.2 | ± | 8.2 | 117.8 | ± | 96.2 | 59.2 | ± | 17.4 | 68.6 | ± | 13.0 |
Calcium (mg/dL) | 14.6 | ± | 0.3 | 14.7 | ± | 0.6 | 14.6 | ± | 0.4 | 14.7 | ± | 1.1 |
Phosphorus (mg/dL) | 8.3 | ± | 0.9 | 8.5 | ± | 0.5 | 8.2 | ± | 0.3 | 8.4 | ± | 0.9 |
Sodium (meq/L) | 142.8 | ± | 2.3 | 142.4 | ± | 2.7 | 143.2 | ± | 0.8 | 143.0 | ± | 4.4 |