Nuclease

Detection limit

Ref

Strand displacement (No nuclease)

462 pM (for miR-21)

[30]

Molecular Beacon (No Nuclease)

About 100 pM

[31]

DSN

426 pM

[32]

DSN

50 pM

[33]

DNase I

9 pM

[14]

DNase I

2.3 pM

[34]

Exonuclease III

21.4 pM

[35]

Exonuclease III

6 pM

[36]

T7 Exonuclease

15 pM

[37]

DSN

37.9 pM

This work