Study ID | No. of patients | Follow-up time | Crizotinib dosage | Chemotheraputic drugs | Trials phase | Blind methods | Ethnicity |
Shaw AT, 2013 [7] | 347 | 12 mo | 250 mg, twice daily | pemetrexed, docetaxel | 3 | × | Multi-races |
Solomon BJ, 2014 [8] | 343 | - | 250 mg, twice daily | pemetrexed, carboplatin | 3 | × | Multi-races |
NCT01639001, 2017 [9] | 207 | - | 250 mg, twice daily | pemetrexed, carboplatin, cisplatin | 3 | √ | Asian |
Zhu LY, 2016 [10] | 86 | 12 mo | 250 mg, twice daily | pemetrexed, docetaxelgemcitabine, carboplatin | 4 | × | Asian |
Wu RH, 2017 [11] | 50 | 12 mo | 250 mg, twice daily | docetaxel | 4 | √ | Asian |
Zhao J, 2015 [12] | 28 | 12 mo | 250 mg, twice daily | docetaxel | 4 | × | Asian |
Ding WB, 2017 [13] | 60 | - | 250 mg, twice daily | docetaxel | 4 | × | Asian |