| 单抗 | 双抗 | ||
CYP2C19*2 GG (n = 157) | CYP2C19*2 AG/AA (n = 129) | CYP2C19*2 GG (n = 156) | CYP2C19*2 AG/AA (n = 128) | |
END(n,%) | 26 (16.6) | 45 (34.9) | 26 (16.7) | 24 (18.8) |
AA诱导的血小板聚集(%) |
|
|
|
|
入院时 | 85.6 ± 14.4 | 92.8 ± 15.3 | 84.9 ± 13.2 | 92.3 ± 11.9 |
7~10天时 | 21.3 ± 9.6 | 33.7 ± 9.5 | 20.9 ± 7.6 | 24.2 ± 8.6 |
ADP诱导的血小板聚集(%) |
|
|
|
|
入院时 | 86.3 ± 13.7 | 93.4 ± 14.7 | 85.8 ± 14.6 | 93.8 ± 12.5 |
7~10天后 | 51.7 ± 11.4 | 72.5 ± 14.6 | 50.9 ± 15.3 | 58.7 ± 10.8 |
血小板–白细胞聚集(%) |
|
|
|
|
入院时白细胞 | 22.3 ± 4.3 | 26.8 ± 4.1 | 22.7 ± 3.9 | 27.1 ± 4.7 |
7~10天后白细胞 | 16.1 ± 4.8 | 23.7 ± 4.5 | 15.7 ± 5.3 | 16.8 ± 6.2 |
入院时中性粒细胞 | 23.1 ± 3.9 | 27.1 ± 4.4 | 23.5 ± 4.2 | 27.3 ± 4.5 |
7~10天后的中性粒细胞 | 17.2 ± 4.3 | 23.8 ± 4.3 | 17.8 ± 5.6 | 18.6 ± 6.1 |
入院时单核细胞 | 28.7 ± 6.2 | 35.5 ± 7.7 | 29.1 ± 7.2 | 33.8 ± 7.4 |
7~10天后单核细胞 | 21.4 ± 4.9 | 31.7 ± 6.7 | 20.9 ± 5.4 | 23.9 ± 6.6 |
入院时淋巴细胞 | 22.6 ± 5.1 | 28.2 ± 6.2 | 22.4 ± 3.7 | 28.5 ± 5.6 |
7~10天后淋巴细胞 | 19.3 ± 6.9 | 26.1 ± 5.3 | 18.9 ± 7.3 | 22.5 ± 5.5 |