Entry | R | Yield [%] | Dr | ee [%] |
1 | 5-H | 89 | 17:1 | 99 |
2 | 5-Me | 63 | 13:1 | 98 |
3 | 5-OMe | 58 | 10:1 | 96 |
4 | 5-F | 86 | >20:1 | 98 |
5 | 5-Cl | 92 | >20:1 | 98 |
6 | 5-Br | 94 | >20:1 | 98 |
7 | 5-I | 91 | >20:1 | 97 |
8 | 5-NO2 | 98 | >20:1 | 98 |
9 | 5-OCF3 | 92 | >20:1 | 96 |
10 | 6-Cl | 94 | >20:1 | 97 |