检测指标

I~II期与III~IV期

AUC (95% CI)

敏感度(%)

特异性(%)

VEGF

0.836 (0.708~0.924)

78.95

85.71

HE4

0.861 (0.779~0.922)

80.56

83.33

CA125

0.850 (0.768~0.912)

76.32

83.33

CA724

0.813 (0.707~0.880)

79.31

66.67

VEGF + HE4

0.840 (0.783~0.888)

82.00

75.00

VEGF + CA125

0.865 (0.757~0.937)

83.67

81.25

VEGF + CA724

0.831 (0.719~0.912)

82.00

75.00

HE4 + CA125

0.880 (0.790~0.942)

74.55

88.59

HE4 + CA724

0.873 (0.792~0.931)

83.33

83.33

CA125 + CA724

0.872 (0.781~0.934)

75.86

88.89

VEGF + HE4 + CA125

0.918 (0.820~0.982)

100

83.43

VEGF + HE4 + CA724

0.869 (0.762~0.940)

85.71

81.25

VEGF + CA125 + CA724

0.872 (0.750~0.949)

81.58

85.71

HE4 + CA125 + CA724

0.897 (0.810~0.953)

83.64

88.89

VEGF + HE4 + CA125 + CA724

0.921 (0.847~0.989)

100

89.43