|
| DCIS | DCIS-MI | DCIS-T1a | P | ||
| (n = 237) | (n = 104) | (n = 213) | ||||
| 年龄 |
|
|
|
| ||
| <50 | 141 (59.5) | 59 (56.7) | 102 (47.9) | 0.042 | ||
| ≥50 | 96 (40.5) | 45 (43.3) | 111 (52.1) |
| ||
| 月经 |
|
|
|
| ||
| 绝经前 | 146 (61.6) | 69 (66.3) | 127 (59.6) | 0.512 | ||
| 绝经后 | 91 (38.4) | 35 (33.7) | 86 (40.4) |
| ||
| 肿瘤大小 |
|
|
|
| ||
| T ≤ 2 | 139 (58.6) | 54 (51.9) | 116 (54.5) | 0.238 | ||
| 2 < T ≤ 5 | 64 (27.0) | 43 (41.3) | 77 (36.2) |
| ||
| T > 5 | 10 (4.2) | 5 (4.8) | 9 (4.2) |
| ||
| 无法获得 | 24 | 2 | 11 |
| ||
| 手术方式 |
|
|
|
| ||
| 改良 | 84 (35.4) | 54 (51.9) | 165 (77.5) | <0.001 | ||
| 保乳 | 48 (20.2) | 19 (18.3) | 15 (7.0) |
| ||
| 单切 | 79 (33.3) | 23 (22.1) | 22 (10.3) |
| ||
| 再造 | 26 (11.0) | 8 (7.7) | 11 (5.2) |
| ||
| 淋巴结情况 |
|
|
|
| ||
| 阳性 | 5 (2.1) | 3 (2.9) | 12 (5.6) | 0.121 | ||
| 阴性 | 231 (97.5) | 99 (95.2) | 201 (94.4) |
| ||
| 无法获得 | 1 | 2 | 0 |
| ||
| ER情况 |
|
|
|
| ||
| 阳性 | 172 (72.6) | 51 (49.0) | 112 (52.6) | <0.001 | ||
| 阴性 | 56 (23.6) | 51 (49.0) | 97 (45.5) |
| ||
| 未知 | 9 | 2 | 4 |
| ||
| PR情况 |
|
|
|
| ||
| 阳性 | 158 (66.7) | 48 (46.2) | 102 (47.9) | <0.001 | ||
| 阴性 | 70 (29.5) | 54 (51.9) | 107 (50.2) |
| ||
| 未知 | 9 | 2 | 4 |
| ||
| HER-2情况 |
|
|
|
| ||
| 阳性 | 46 (19.4) | 30 (28.8) | 46 (21.6) | 0.197 | ||
| 阴性 | 181 (76.4) | 73 (70.2) | 163 (76.5) |
| ||
| 未知 | 10 | 1 | 4 |
| ||
| Ki-67 |
|
|
|
| ||
| <14 | 132 (55.7) | 37 (35.6) | 78 (36.6) | <0.001 | ||
| ≥14 | 89 (37.6) | 64 (61.5) | 127 (59.6) |
| ||
| 无法获得 | 16 | 3 | 8 |
| ||
| 分子分型 |
|
|
|
| ||
| HER-2阳性(HR阴性) | 27 (11.4) | 21 (20.2) | 36 (16.9) | <0.001 | ||
| HER-2阳性(HR阳性) | 19 (8.0) | 8 (7.7) | 10 (4.7) |
| ||
| 三阴型 | 29 (12.2) | 25 (24.0) | 61 (28.6) |
| ||
| Luminal A型(HER-2阴性) | 100 (42.2) | 26 (25.0) | 35 (16.4) |
| ||
| Luminal B型(HER-2阴性) | 5 (2.1) | 4 (3.8) | 5 (2.3) |
| ||
| 未知 | 57 | 20 | 66 |
| ||